Drug Type Chemical drugs |
Synonyms Co-methylcobalamin, MeCbl, Mecobalamin (JP17/USAN) + [40] |
Target |
Action stimulants |
Mechanism DNMT1 stimulants(DNA (cytosine-5)-methyltransferase 1 stimulants), Epigenetic drug |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date Japan (16 Apr 1987), |
RegulationOrphan Drug (United States), Orphan Drug (Japan) |
Molecular FormulaC63H91CoN13O14P |
InChIKeyROWAQRTUUUIVDZ-FGIXMQGJSA-M |
CAS Registry13422-55-4 |
Start Date01 Jan 2026 |
Sponsor / Collaborator |
Start Date15 Sep 2025 |
Sponsor / Collaborator |
Start Date01 Sep 2025 |
Sponsor / Collaborator |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D03246 | Mecobalamin |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Amyotrophic Lateral Sclerosis | Japan | 24 Sep 2024 | |
Peripheral Nervous System Diseases | Japan | 16 Apr 1987 | |
Neuralgia | China | - | |
Neuritis | China | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Methylmalonic Acidemia | Preclinical | United States | 22 Oct 2024 |
Study | Phase | Population | Analyzed Enrollment | Group | Results | Evaluation | Publication Date |
---|
Phase 3 | 130 | mejxmljqgm(ipknbmipzc) = thiixwmyyz qnqmwhrimu (bksjkldzlo ) | Positive | 09 May 2022 | |||
Placebo | mejxmljqgm(ipknbmipzc) = oglumbnrnt qnqmwhrimu (bksjkldzlo ) | ||||||
Phase 2 | - | bzrxnlywrd(jdxqmqqwhr) = hbmrzwvicu tqwgmkheyf (ixtzesznxj ) | Positive | 19 Jul 2021 | |||
bzrxnlywrd(jdxqmqqwhr) = ntrbgoxwhd tqwgmkheyf (ixtzesznxj ) |