Last update 01 Nov 2024

Ninerafaxstat

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
IMB1018972 trihydrochloride monohydrate
+ [2]
Target
Mechanism
HADHB inhibitors(hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta inhibitors), Partial fatty acid oxidation inhibitors
Inactive Indication
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Structure

Molecular FormulaC22H29N3O5
InChIKeyAGVJLPKGBKSLKF-UHFFFAOYSA-N
CAS Registry2254741-41-6

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Coronary Artery DiseasePhase 2
FI
23 Apr 2021
Coronary Artery DiseasePhase 2
DK
23 Apr 2021
Coronary Artery DiseasePhase 2
SE
23 Apr 2021
IschemiaPhase 2
SE
23 Apr 2021
IschemiaPhase 2
DK
23 Apr 2021
IschemiaPhase 2
FI
23 Apr 2021
Diabetes Mellitus, Type 2Phase 2
GB
21 Apr 2021
Diabetic CardiomyopathiesPhase 2
GB
21 Apr 2021
Heart failure with normal ejection fractionPhase 2
GB
21 Apr 2021
ObesityPhase 2
GB
21 Apr 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
NEWS
ManualManual
Phase 2
58
pwcjufwtkm(fcwznewoca) = Imbria hits safety benchmark in phase 2 heart failure test as early efficacy data buoy late-stage plans lsxbfvcpys (xqoobmzsvv )
Positive
13 Nov 2023
placebo
Phase 2
-
(pugntdjxar) = met the safety and tolerability goals zxkyhxvpfk (aokaoopdim )
Positive
07 Nov 2023
Phase 2
21
bokgdwignh(hijwwrptql) = kigtfzobfr gxryqewprn (srzcznedrc )
Positive
22 Aug 2022
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Core Patent

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Clinical Trial

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Approval

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Regulation

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