Drug Type Small molecule drug |
Synonyms IMB1018972 trihydrochloride monohydrate + [2] |
Target |
Mechanism HADHB inhibitors(hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta inhibitors), Partial fatty acid oxidation inhibitors |
Active Indication |
Inactive Indication |
Originator Organization Imbria Pharmaceuticals, Inc.Startup |
Active Organization Imbria Pharmaceuticals, Inc.Startup |
Inactive Organization- |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
Molecular FormulaC22H29N3O5 |
InChIKeyAGVJLPKGBKSLKF-UHFFFAOYSA-N |
CAS Registry2254741-41-6 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Coronary Artery Disease | Phase 2 | FI | Imbria Pharmaceuticals, Inc.Startup | 23 Apr 2021 |
Coronary Artery Disease | Phase 2 | DK | Imbria Pharmaceuticals, Inc.Startup | 23 Apr 2021 |
Coronary Artery Disease | Phase 2 | SE | Imbria Pharmaceuticals, Inc.Startup | 23 Apr 2021 |
Ischemia | Phase 2 | SE | Imbria Pharmaceuticals, Inc.Startup | 23 Apr 2021 |
Ischemia | Phase 2 | DK | Imbria Pharmaceuticals, Inc.Startup | 23 Apr 2021 |
Ischemia | Phase 2 | FI | Imbria Pharmaceuticals, Inc.Startup | 23 Apr 2021 |
Diabetes Mellitus, Type 2 | Phase 2 | GB | Imbria Pharmaceuticals, Inc.Startup | 21 Apr 2021 |
Diabetic Cardiomyopathies | Phase 2 | GB | Imbria Pharmaceuticals, Inc.Startup | 21 Apr 2021 |
Heart failure with normal ejection fraction | Phase 2 | GB | Imbria Pharmaceuticals, Inc.Startup | 21 Apr 2021 |
Obesity | Phase 2 | GB | Imbria Pharmaceuticals, Inc.Startup | 21 Apr 2021 |
NEWS Manual | Phase 2 | 58 | pwcjufwtkm(fcwznewoca) = Imbria hits safety benchmark in phase 2 heart failure test as early efficacy data buoy late-stage plans lsxbfvcpys (xqoobmzsvv ) | Positive | 13 Nov 2023 | ||
placebo | |||||||
IMPROVE-HCM (NEWS) Manual | Phase 2 | - | (pugntdjxar) = met the safety and tolerability goals zxkyhxvpfk (aokaoopdim ) View more | Positive | 07 Nov 2023 | ||
Phase 2 | 21 | bokgdwignh(hijwwrptql) = kigtfzobfr gxryqewprn (srzcznedrc ) View more | Positive | 22 Aug 2022 |