Last update 01 Nov 2024

JSKN-033

Overview

Basic Info

Drug Type
Antibody drug conjugate (ADC)
Synonyms
JSKN003/Envafolimab
Target
HER2 x PDL1
Mechanism
HER2 antagonists(Receptor protein-tyrosine kinase erbB-2 antagonists), PDL1 inhibitors(Programmed death-ligand 1 inhibitors)
Therapeutic Areas
Neoplasms
Active Indication
HER2 Positive Solid TumorsSolid tumor
Inactive Indication-
Originator Organization
Jiangsu Alphamab Biopharmaceuticals Co., LtdJiangsu Alphamab Biopharmaceuticals Co., Ltd
Active Organization
Jiangsu Alphamab Biopharmaceuticals Co., LtdJiangsu Alphamab Biopharmaceuticals Co., Ltd
Inactive Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
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Structure

Molecular FormulaC38H43N9O8
InChIKeyQODRVHFOPFCZOM-IUDBTDONSA-N
CAS Registry-
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Related

1
Clinical Trials associated with JSKN-033
NCT06226766 / RecruitingPhase 1/2
Phase I/II Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of JSKN033 in Patients With Advanced or Metastatic Solid Malignant Tumors
100 Clinical Results associated with JSKN-033
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100 Translational Medicine associated with JSKN-033
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100 Patents (Medical) associated with JSKN-033
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100 Deals associated with JSKN-033
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HER2 Positive Solid TumorsPhase 2
AU
Jiangsu Alphamab Biopharmaceuticals Co., LtdJiangsu Alphamab Biopharmaceuticals Co., Ltd
26 Mar 2024
Solid tumorPhase 2
AU
Jiangsu Alphamab Biopharmaceuticals Co., LtdJiangsu Alphamab Biopharmaceuticals Co., Ltd
18 Jan 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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