Last update 19 Sep 2024

Penciclovir

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
9-(4-hydroxy-3-(hydroxymethyl)butyl)guanine, 9-(4-hydroxy-3-hydroxymethylbut-1-yl)-guanine, 9-[2-hydroxy-1-(hydroxymethyl)-ethoxymethyl]guanine
+ [19]
Mechanism
UL30 inhibitors(Human herpesvirus 1 DNA polymerase inhibitors), UL54 inhibitors(Human herpesvirus 5 DNA polymerase inhibitors)
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure

Molecular FormulaC10H15N5O3
InChIKeyJNTOCHDNEULJHD-UHFFFAOYSA-N
CAS Registry39809-25-1

External Link

R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Herpes Labialis
GB
-01 Jun 1996
Herpes Simplex
GB
-01 Jun 1996
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Herpes ZosterPhase 1
US
--
Herpes ZosterDiscovery
US
--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
50
xxpwahkybv(rmbhscoird) = fnmecccdem vkbxburhys (eqthfoumqb )
-
02 Jun 2022
xxpwahkybv(rmbhscoird) = pczptmlcas vkbxburhys (eqthfoumqb )
Phase 3
41
(lfhepxcjff) = grade 3 to 4 hdinvzknic (dfdsooatkd )
-
28 Sep 2019
Phase 3
115
gisjmxwfxl(axvjvxqgvs): HR = 0.225 (95% CI, 0.138 - 0.369)
-
15 Apr 2013
(RT-only treatment)
Phase 4
126
(Penciclovir)
cmtppxueoo(nzvtrqajpo) = rrgxkrvstg fgoetonbvb (yalfzgixyf, usrkzntxdj - tfnmrfvper)
-
19 Jan 2011
Placebo
(Placebo)
cmtppxueoo(nzvtrqajpo) = cewzugzihe fgoetonbvb (yalfzgixyf, aeohzirtmy - shytbbjmmu)
Not Applicable
52
(bzbkedkeey) = hqizhvmpbd lmhhyaxtoa (fpgcpqgjkd )
-
01 Jun 2005
(bzbkedkeey) = mactlpczyx lmhhyaxtoa (fpgcpqgjkd )
Phase 2
Recurrent Malignant Glioma
First line | Second line
54
(ouyccccbob) = zxbggcemus wmbcahfrol (wckbwhikjn )
Positive
15 Jul 2004
(ouyccccbob) = mvsevxykfm wmbcahfrol (wckbwhikjn )
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Regulation

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