Drug Type Small molecule drug |
Synonyms MAC-321, MAC-321 IV, TL 00139 + [3] |
Target |
Action inhibitors |
Mechanism Tubulin inhibitors |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhasePendingPhase 2 |
First Approval Date- |
Regulation- |
Molecular FormulaC44H55NO16 |
InChIKeyXIVMHSNIQAICTR-DMUFGCTNSA-N |
CAS Registry393101-41-2 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Mesothelioma, Malignant | Phase 2 | United States | 01 Mar 2008 | |
Advanced Colorectal Adenocarcinoma | Phase 2 | - | 27 Jun 2003 | |
Colonic Cancer | Phase 2 | - | 27 Jun 2003 | |
Rectal Cancer | Phase 2 | - | 27 Jun 2003 | |
Non-Small Cell Lung Cancer | Phase 2 | United States | 25 Jun 2003 |
Phase 1 | 11 | dccetwnqet(hdugnglnvx) = zbhehegjto grgmsjtaxv (nrwanaxkur ) | - | 20 May 2009 | |||
Phase 1 | 32 | kwpznpfyoj(ekbyklhlmv) = pjvgsoakfi jekxtqckcg (geczorcwox ) View more | - | 20 Jun 2006 | |||
Phase 1 | 18 | fuxxanudit(naegxurdpc) = Other common toxicities included grade 1–2 fatigue and grade 1–2 diarrhea icfbuikqpo (tqkavynetb ) | Positive | 15 Jul 2004 |