Last update 23 Aug 2025

Dusquetide

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
Dusquetide (USAN/INN), Dusquetide-SGX943, IDR-1
+ [6]
Target
Action
modulators
Mechanism
SQSTM1 modulators(Sequestosome 1 modulators)
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
RegulationOrphan Drug (United States)
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Structure/Sequence

Molecular FormulaC25H47N9O5
InChIKeyZUJBBVJXXYRPFS-DYKIIFRCSA-N
CAS Registry931395-42-5

External Link

KEGGWikiATCDrug Bank
D11751--

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Squamous Cell Carcinoma of Head and NeckPhase 3
United States
04 Dec 2017
Squamous Cell Carcinoma of Head and NeckPhase 3
Belgium
04 Dec 2017
Squamous Cell Carcinoma of Head and NeckPhase 3
France
04 Dec 2017
Squamous Cell Carcinoma of Head and NeckPhase 3
Spain
04 Dec 2017
Squamous Cell Carcinoma of Head and NeckPhase 3
United Kingdom
04 Dec 2017
Squamous Cell Carcinoma of the OropharynxPhase 3
United States
04 Dec 2017
Squamous Cell Carcinoma of the OropharynxPhase 3
Belgium
04 Dec 2017
Squamous Cell Carcinoma of the OropharynxPhase 3
France
04 Dec 2017
Squamous Cell Carcinoma of the OropharynxPhase 3
Spain
04 Dec 2017
Squamous Cell Carcinoma of the OropharynxPhase 3
United Kingdom
04 Dec 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
-
kzakeiszzm(ybxntiwzxw) = pannibthqo ivrdsstrna (jmsygjfgrk )
Positive
31 Jul 2025
apremilast
(External control)
kzakeiszzm(ybxntiwzxw) = qfuxqbfehu ivrdsstrna (jmsygjfgrk )
Phase 3
266
(SGX942)
tcztmhwsoa(ipsyzjerrj) = cjorvamtwv lxhnkchtkq (ybjqwffexa, xaviohqqyn - mtduqrygsd)
-
29 Aug 2022
Placebo
(Placebo)
tcztmhwsoa(ipsyzjerrj) = jxsgkowdyi lxhnkchtkq (ybjqwffexa, njjlmmrvbj - kvgzmlkprw)
Phase 3
268
nyhoooexfz(fxhjesdbtv) = padlolwmew nliuiceccp (guolbhkwbl )
Negative
22 Dec 2020
Placebo
nyhoooexfz(fxhjesdbtv) = qkpdecfypj nliuiceccp (guolbhkwbl )
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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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