Last update 01 Aug 2026

SOS1 PROTAC 8l(Shanghai Institute of Materia Medica)

Overview

Basic Info

Drug Type
Proteolysis-targeting chimeras (PROTAC)
Synonyms-
Target
SOS1
Action
degraders
Mechanism
SOS1 degraders(Son of sevenless homolog 1 degraders)
Therapeutic Areas
Neoplasms
Active Indication
KRAS mutation-related tumors
Inactive Indication-
Originator Organization
University of Chinese Academy of SciencesUniversity of Chinese Academy of SciencesShanghai Institute of Materia Medica Chinese Academy of SciShanghai Institute of Materia Medica Chinese Academy of Sci
Active Organization
Shanghai Institute of Materia Medica Chinese Academy of SciShanghai Institute of Materia Medica Chinese Academy of SciUniversity of Chinese Academy of SciencesUniversity of Chinese Academy of Sciences
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with SOS1 PROTAC 8l(Shanghai Institute of Materia Medica)
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100 Translational Medicine associated with SOS1 PROTAC 8l(Shanghai Institute of Materia Medica)
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100 Patents (Medical) associated with SOS1 PROTAC 8l(Shanghai Institute of Materia Medica)
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100 Deals associated with SOS1 PROTAC 8l(Shanghai Institute of Materia Medica)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
KRAS mutation-related tumorsPreclinical
China
Shanghai Institute of Materia Medica Chinese Academy of SciShanghai Institute of Materia Medica Chinese Academy of Sci
10 Mar 2023
KRAS mutation-related tumorsPreclinical
China
University of Chinese Academy of SciencesUniversity of Chinese Academy of Sciences
10 Mar 2023
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Clinical Result

Indication
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Approval

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Regulation

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