Last update 01 Nov 2024

SOS1

Basic Info

Synonyms
GF1, GINGF, gingival fibromatosis, hereditary, 1
+ [6]
Introduction
Promotes the exchange of Ras-bound GDP by GTP (PubMed:8493579). Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF (PubMed:17339331). Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity (By similarity).

Analysis

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