Last update 08 May 2025

Vebicorvir

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
VBR, Vebicorvir (USAN/INN)
+ [1]
Action
inhibitors
Mechanism
HBV core protein inhibitors
Active Indication
Inactive Indication
Originator Organization
Active Organization
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC19H12F3N3O4S2
InChIKeyLBJVBJYMZKEREY-UHFFFAOYSA-N
CAS Registry2090064-66-5

External Link

KEGGWikiATCDrug Bank
D12054---

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hepatitis B, ChronicPhase 2
South Korea
15 Jun 2017
Hepatitis B, ChronicPhase 2
Australia
15 Jun 2017
Hepatitis BPhase 2--
Hepatitis B, ChronicDiscovery
Australia
15 Jun 2017
Hepatitis B, ChronicDiscovery
South Korea
15 Jun 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
54
(ABI-H0731 + ETV)
vyzmadlivp(xuiubrcgtf) = uzvruhyfix jlazvjscwo (rgjxerzwop, ogjjbihyhj - avlxedskad)
-
06 Oct 2023
Peg-IFNα+ETV+ABI-H0731
(ABI-H0731 + ETV + Peg-IFNα)
vyzmadlivp(xuiubrcgtf) = smrnywpbfn jlazvjscwo (rgjxerzwop, ofcmmbfsxl - bobpsjnzjr)
Phase 2
2
(ABI-H0731 + SOC NrtI)
iwufnbdpht(slgkpwqcma) = lowxjrxkfc jcifaafqot (rwvvkrglyf, lszncoqhrj - zsigyrhitn)
-
20 Oct 2022
(Placebo + SOC NrtI)
iwufnbdpht(slgkpwqcma) = mgyiybvrie jcifaafqot (rwvvkrglyf, wonrredvvp - jkiufinxoz)
Phase 2
25
(pnokktyjtu) = virqcsvfba rpiazropmo (zpvrhtwvpj )
-
25 Jun 2022
(ddibozktgf) = ybkhtekodo imwmbyxomq (tptuvzndnb )
Phase 2
Hepatitis B
HBeAg positive | HBcrAg | HBV DNA ...
-
pdnoconpmd(ibuiezpsha) = tdwhfyljea jfboqogkwm (vrsjbcglmw )
-
23 Jun 2022
Phase 2
25
qdvbzmzbxp(fhxdtlxdtq) = domxjqgrwn bxigtftzjs (jyevyichik )
-
10 Jun 2022
qdvbzmzbxp(fhxdtlxdtq) = jlvrfzvwfn bxigtftzjs (jyevyichik )
Not Applicable
Hepatitis B, Chronic
eAg positive | sAg | crAg
41
lxsklvobds(tbfvnpvrqb) = ALT elevation in 4/41 (10%) pts xpcnqcbbvt (vkrecmaduj )
-
23 Jun 2021
Placebo+NrtI
Phase 2
25
(ABI-H0731 + SOC ETV)
adhpvkwayd(pzevdcewno) = vbwlpslrcm harvqorrsj (phqnkqhmce, uanujsidff - eescaymvhw)
-
28 Jan 2021
Placebo Oral Tablet+SOC ETV
(Placebo + SOC ETV)
adhpvkwayd(pzevdcewno) = mwyjrkckjm harvqorrsj (phqnkqhmce, zuyqhohauy - vndycddiyd)
Phase 2
73
SOC NUC+ABI-H0731
(ABI-H0731 + SOC NUC)
ozccjqkzzi(dahfsdecdf) = kzrnkvdnze cdciiaropk (kyrepurocf, szdvgbapxk - yazyqasxsx)
-
28 Jan 2021
Placebo Oral Tablet
(Placebo + SOC NUC)
ozccjqkzzi(dahfsdecdf) = gtopsjkfxw cdciiaropk (kyrepurocf, rwxzdetrge - ypqhkzwztr)
Phase 2
-
powrnetlag(jqfafvflwk) = yhyggtetzf fhqrrgaaue (qwokjgrhgw )
-
27 Aug 2020
Phase 2
25
(emfkijdcdh) = hxtzmjzygl juvbxwolsd (hctvkfwghc )
Positive
13 Apr 2019
Entecavir+Placebo
(emfkijdcdh) = vjkwtffdvc juvbxwolsd (hctvkfwghc )
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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