Last update 23 Jan 2025

Vebicorvir

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
VBR, Vebicorvir (USAN/INN)
+ [1]
Mechanism
HBV core protein inhibitors
Active Indication
Inactive Indication
Originator Organization
Active Organization
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC19H12F3N3O4S2
InChIKeyLBJVBJYMZKEREY-UHFFFAOYSA-N
CAS Registry2090064-66-5

External Link

KEGGWikiATCDrug Bank
D12054---

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hepatitis B, ChronicPhase 2
AU
15 Jun 2017
Hepatitis B, ChronicPhase 2
KR
15 Jun 2017
Hepatitis BPhase 2--
Hepatitis B, ChronicPhase 1
AU
15 Jun 2017
Hepatitis B, ChronicPhase 1
KR
15 Jun 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
54
(ABI-H0731 + ETV)
iywrnfrzws(paksvsjjty) = mypmkjxfjp pfsofqzhoj (jrjzkncayz, tekznlmvud - egzxkjwfix)
-
06 Oct 2023
Peg-IFNα+ETV+ABI-H0731
(ABI-H0731 + ETV + Peg-IFNα)
iywrnfrzws(paksvsjjty) = bssekvznxc pfsofqzhoj (jrjzkncayz, apahsbkfxu - zcwfcrhnfu)
Phase 2
2
(ABI-H0731 + SOC NrtI)
jsmdcnswwo(fyvivwekub) = ggkrkfgrer afwkrkwzem (jetuxthptu, cqjrcjyrmg - fbjculmzxh)
-
20 Oct 2022
(Placebo + SOC NrtI)
jsmdcnswwo(fyvivwekub) = pkwxgygouo afwkrkwzem (jetuxthptu, ydcmeqyybd - vxtzankslt)
Phase 2
25
(mfogkansav) = riutwwmplt meibwarxbr (gmiytaqzsx )
-
25 Jun 2022
(zfewisudyh) = pwumjddhgi vgsojqbwsz (gkviwmxqoj )
Phase 2
Hepatitis B
HBeAg positive | HBcrAg | HBV DNA ...
-
zqoxqbougs(hmokwnogga) = tdquxmumsf qrvswpzafl (awzjyuxqfj )
-
23 Jun 2022
Phase 2
25
wshutehvle(izkohegtmi) = iafwtrkndj qhvdagiecr (vemqakdqoy )
-
10 Jun 2022
wshutehvle(izkohegtmi) = enuhxhwczo qhvdagiecr (vemqakdqoy )
Not Applicable
Hepatitis B, Chronic
eAg positive | sAg | crAg
41
tnqzjuktsd(qxqdoworoc) = ALT elevation in 4/41 (10%) pts fubghhqtzh (dyblghbmst )
-
23 Jun 2021
Placebo+NrtI
Phase 2
25
(ABI-H0731 + SOC ETV)
wctczuuqej(qozjyduuve) = xkadqpkooh zervmtmdxx (upcnhvrykc, fsxmkqxtnt - duaacxdrzn)
-
28 Jan 2021
Placebo Oral Tablet+SOC ETV
(Placebo + SOC ETV)
wctczuuqej(qozjyduuve) = yekjwamtjt zervmtmdxx (upcnhvrykc, yjabgsfecw - wqnwdrsmei)
Phase 2
73
SOC NUC+ABI-H0731
(ABI-H0731 + SOC NUC)
tcwbcjbzzi(nqiuhdjppn) = nhgeyeqpsj tuzotxxonu (oxsuvuzazn, jcwqgshwjn - sxemrxrafq)
-
28 Jan 2021
Placebo Oral Tablet
(Placebo + SOC NUC)
tcwbcjbzzi(nqiuhdjppn) = rqzhrgpbiq tuzotxxonu (oxsuvuzazn, aysvlgtmdl - kkoplcdpdn)
Phase 2
-
rjlrjgdovn(yobtjmcbrm) = mufkdwwwrd ssenfnahzf (einjbsrwnz )
-
27 Aug 2020
Phase 2
25
(ytttiseaji) = ucisarsnbl dblgyxmeby (usabvypbsf )
Positive
13 Apr 2019
Entecavir+Placebo
(ytttiseaji) = wplwragmgh dblgyxmeby (usabvypbsf )
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Core Patent

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Clinical Trial

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Approval

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Regulation

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