Last update 04 Dec 2024

Acetaminophen/Dexbrompheniramine Maleate/Pseudoephedrine Sulfate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Drixoral Plus
Target
ADRA1 x ADRA2 x COX x Histamine receptor x β1-adrenergic receptor x β2-adrenergic receptor x β3-adrenergic receptor
Mechanism
ADRA1 agonists(Adrenergic receptor alpha-1 agonists), ADRA2 agonists(Adrenergic receptors alpha-2 agonists), COX inhibitors(Cyclooxygenases inhibitors)
Therapeutic Areas
Immune System DiseasesInfectious DiseasesNervous System Diseases+ [4]
Active Indication-
Inactive Indication
FeverHeadacheNasal Obstruction+ [3]
Originator Organization
Merck & Co., Inc.Merck & Co., Inc.
Active Organization-
Inactive Organization
Schering-Plough Corp.
Drug Highest PhaseWithdrawn
First Approval Date
US (22 May 1987),
FeverHeadacheNasal Obstruction+ [3]
Regulation-
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Structure

Molecular FormulaC8H9NO2
InChIKeyRZVAJINKPMORJF-UHFFFAOYSA-N
CAS Registry103-90-2
View All Structures (3)

Related

100 Clinical Results associated with Acetaminophen/Dexbrompheniramine Maleate/Pseudoephedrine Sulfate
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100 Translational Medicine associated with Acetaminophen/Dexbrompheniramine Maleate/Pseudoephedrine Sulfate
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100 Patents (Medical) associated with Acetaminophen/Dexbrompheniramine Maleate/Pseudoephedrine Sulfate
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100 Deals associated with Acetaminophen/Dexbrompheniramine Maleate/Pseudoephedrine Sulfate
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Fever
US
Schering-Plough Corp.
22 May 1987
Headache
US
Schering-Plough Corp.
22 May 1987
Nasal Obstruction
US
Schering-Plough Corp.
22 May 1987
Pain
US
Schering-Plough Corp.
22 May 1987
Rhinitis, Allergic, Seasonal
US
Schering-Plough Corp.
22 May 1987
Urticaria
US
Schering-Plough Corp.
22 May 1987
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Approval

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Regulation

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