Last update 01 Nov 2024

CBA-1205

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Target
DLK1
Mechanism
DLK1 inhibitors(Protein delta homolog 1 inhibitors)
Therapeutic Areas
NeoplasmsDigestive System Disorders
Active Indication
Hepatocellular Carcinoma
Inactive Indication-
Originator Organization
LivTech, Inc.LivTech, Inc.Chiome Bioscience, Inc.Chiome Bioscience, Inc.
Active Organization
Chiome Bioscience, Inc.Chiome Bioscience, Inc.
Inactive Organization
Kyowa Kirin Co., Ltd.Kyowa Kirin Co., Ltd.ADC Therapeutics SAADC Therapeutics SA
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

3
Clinical Trials associated with CBA-1205
JPRN-jRCT2080225288 / RecruitingPhase 1
Phase I study of CBA-1205
JPRN-JapicCTI-205384 / RecruitingPhase 1
Phase I study of CBA-1205
NCT06636435 / RecruitingPhase 1
A Phase I, First in Human Study of CBA-1205, Anti-DLK1 Monoclonal Antibody in Patients with Advanced Solid Tumors and Hepatocellular Carcinoma (HCC)
100 Clinical Results associated with CBA-1205
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100 Translational Medicine associated with CBA-1205
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100 Patents (Medical) associated with CBA-1205
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100 Deals associated with CBA-1205
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hepatocellular CarcinomaPhase 1
JP
Chiome Bioscience, Inc.Chiome Bioscience, Inc.
01 Jun 2020
NeoplasmsPhase 1
JP
Kyowa Kirin Co., Ltd.Kyowa Kirin Co., Ltd.
01 Oct 2008
Solid tumorPreclinical
JP
Chiome Bioscience, Inc.Chiome Bioscience, Inc.
07 Jul 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
AACR2023
ManualManual
Phase 1
HR-positive/HER2-low Solid Tumors
First line
22
(nhztdaklps) = eswtlqkivl uuowtsjusp (auzibvypuk )
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Positive
14 Apr 2023
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Clinical Trial

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Approval

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Regulation

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