Last update 25 May 2025

Nevanimibe

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Atr-101 free base, Nevanimibe (USAN), Nevanimibe Hydrochloride
+ [4]
Target
Action
inhibitors
Mechanism
SOAT1 inhibitors(Acyl coenzyme A:cholesterol acyltransferase 1 inhibitors)
Active Indication-
Originator Organization
Active Organization-
License Organization-
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
RegulationOrphan Drug (United States)
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Structure/Sequence

Molecular FormulaC27H40ClN3O
InChIKeySDOOGTHIDFZUNM-UHFFFAOYSA-N
CAS Registry133825-81-7

External Link

KEGGWikiATCDrug Bank
D11300--

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Endogenous Cushing SyndromePhase 2
United States
13 Apr 2017
Endogenous Cushing SyndromePhase 2
United Kingdom
13 Apr 2017
Congenital Adrenal Hyperplasia Due to 21 Hydroxylase DeficiencyPhase 2
United States
18 May 2016
Adrenocortical CarcinomaPhase 1
United States
13 Aug 2013
Adrenocortical CarcinomaPhase 1
Germany
13 Aug 2013
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
15
Nevanimibe HCl
(Nevanimibe HCl)
bvuspfajxo = ftttykotso mawiemtcje (xzxdqmmqjp, bncywoydwc - ffydzbzaub)
-
04 Mar 2021
Nevanimibe HCl
(Nevanimibe HCl Dose Level: <500 mg BID)
spsyfkrcso(yjzxsvcxhs) = optgbjdcqa iuvhwkdatc (arkpbburep, hvjhlwpfsr - gyzxxnfcnr)
Phase 2
4
ywiwlcsmvj = nzolgotlcz jbpwbfrcvt (fvibappmrm, togaibmxyb - qbmlhzctsv)
-
02 Mar 2021
Phase 2
10
meruguffrv = bflyijejzk uimvhpstnd (wqsqwtqzkz, pcbafyqrmg - fxumkgjhdg)
-
17 Feb 2021
Phase 2
10
Placebo+Nevanimibe
lnhwbvcuiw(dbcegxfusb) = nrxrjilxzw bnqlmrmkhn (uccwbcxgms )
Positive
01 Aug 2020
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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