Delving into the Latest Updates on Wenjing Decoction with Synapse

Overview

Basic Info

Drug Type

Herbal medicine

Synonyms

コタロー温経湯エキス細粒

Target-

Action-

Mechanism-

Therapeutic Areas

Nervous System DiseasesCongenital DisordersSkin and Musculoskeletal Diseases+ [2]

Active Indication

AndropauseDysmenorrheaEczema+ [8]

Inactive Indication-

Originator Organization

Kotaro pharmaceutical Co Ltd.

Active Organization

Kotaro pharmaceutical Co Ltd.

Tsumura & Co.

Inactive Organization-

Drug Highest PhaseApproved

First Approval Date

Japan (16 Aug 1986),

AndropauseDysmenorrheaEczema+ [8]

Regulation-

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One hundred twenty-two patients with spontaneous angina pectoris (SAP) were randomly divided into treated group (82 cases) and control group (40 cases), and treated with Wenxin decoction and isosorbide dinitrate respectively. Results showed that in treated group the total effective rate of SAP was 95.12% and that of electrocardiographic findings were 74.39%. These results were all superior to those of control group (P < 0.01). Moreover, results of extracorporeal thrombosis test showed after Wenxin decoction treatment, the length of thrombus decreased from 23.56 +/- 5.47 mm to 20.04 +/- 5.17 mm, the wet weight of it decreased from 92.65 +/- 18.45 mg to 76.94 +/- 15.08 mg and the dry weight from 21.76 +/- 7.30 mg to 16.90 +/- 5.35 mg. The submaximal exercise test revealed an increase of exercise time from 474.66 +/- 96.33 seconds to 548.83 +/- 99.93 seconds, increase of acting quantity from 104.16 +/- 19.65 W to 123.61 +/- 24.96 W and a decrease of ST segment depression from 0.183 +/- 0.041 mV to 0.139 +/- 0.038 mV. These results suggested that Wenxin decoction is valuable in treating SAP.

100 Deals associated with Wenjing Decoction

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R&D Status

10 top approved records.

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Indication	Country/Location	Organization	Date
Andropause	Japan	Kotaro pharmaceutical Co Ltd.	16 Aug 1986
Andropause	Japan	Tsumura & Co.	16 Aug 1986
Dysmenorrhea	Japan	Tsumura & Co.	16 Aug 1986
Eczema	Japan	Tsumura & Co.	16 Aug 1986
Hot Flashes	Japan	Kotaro pharmaceutical Co Ltd.	16 Aug 1986
Keratoderma, Palmoplantar	Japan	Kotaro pharmaceutical Co Ltd.	16 Aug 1986
Leukorrhea	Japan	Kotaro pharmaceutical Co Ltd.	16 Aug 1986
Low Back Pain	Japan	Kotaro pharmaceutical Co Ltd.	16 Aug 1986
Menorrhagia	Japan	Kotaro pharmaceutical Co Ltd.	16 Aug 1986
Menstruation Disturbances	Japan	Kotaro pharmaceutical Co Ltd.	16 Aug 1986
Menstruation Disturbances	Japan	Tsumura & Co.	16 Aug 1986
Neurotic Disorders	Japan	Tsumura & Co.	16 Aug 1986
Sleep Initiation and Maintenance Disorders	Japan	Tsumura & Co.	16 Aug 1986