Last update 14 Feb 2026

MK-8504

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
MK 8504
Target
RT
Action
inhibitors
Mechanism
RT inhibitors(Viral reverse transcriptase inhibitors)
Therapeutic Areas
Immune System DiseasesInfectious DiseasesUrogenital Diseases
Active Indication-
Inactive Indication
HIV Seropositivity
Originator Organization
Merck Sharp & Dohme Corp.Merck Sharp & Dohme Corp.
Active Organization-
Inactive Organization
Merck Sharp & Dohme Corp.Merck Sharp & Dohme Corp.
License Organization-
Drug Highest PhasePendingPhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with MK-8504
NCT03188523
/ CompletedPhase 1
A Single-Dose Clinical Trial to Study the Safety, Tolerability, Pharmacokinetics, and Anti-Retroviral Activity of MK-8504 Monotherapy in Anti-Retroviral Therapy (ART)-Naïve, HIV-1 Infected Patients
100 Clinical Results associated with MK-8504
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100 Translational Medicine associated with MK-8504
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100 Patents (Medical) associated with MK-8504
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100 Deals associated with MK-8504
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HIV SeropositivityPhase 1
Germany
Merck Sharp & Dohme Corp.Merck Sharp & Dohme Corp.
08 Sep 2017
HIV SeropositivityPhase 1
United Kingdom
Merck Sharp & Dohme Corp.Merck Sharp & Dohme Corp.
08 Sep 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
NCT03188523 (8504-002 | MK-8504-002, CTgov)
Phase 1
HIV Infections | HIV Seropositivity
12
(MK-8504 100 mg (Panel A))
iwzegbyuyg(xqbhsyprxt) = klqmcmogpt hfwbbwinex (ulnmmrdwzg, phobwkwrpz - puxgmtewhq)
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-
15 Jul 2019
(MK-8504 240 mg (Panel B))
iwzegbyuyg(xqbhsyprxt) = bzlvcmudoi hfwbbwinex (ulnmmrdwzg, kfgryxvcyg - czkseabwur)
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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