Last update 04 Nov 2024

Fexofenadine Hydrochloride/Pseudoephedrine Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)butyl)-alpha,alpha-dimethylbenzeneacetic acid, Allegra-D, Carboxyterfenadine
+ [14]
Mechanism
H1 receptor antagonists(Histamine H1 receptor antagonists), α-adrenergic receptor agonists(Alpha adrenergic receptor agonists)
Inactive Indication
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure

Molecular FormulaC10H16ClNO
InChIKeyBALXUFOVQVENIU-KXNXZCPBSA-N
CAS Registry345-78-8
View All Structures (2)

R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Rhinitis, Allergic
JP
25 Dec 2012
Rhinitis, Allergic
JP
25 Dec 2012
Chronic Urticaria
US
24 Dec 1997
Rhinitis, Allergic, Seasonal
US
24 Dec 1997
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Seasonal rhinitisPhase 3
CA
17 Sep 2018
AsthmaPhase 3
US
01 Feb 2002
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
255
placebo to fexofenadine+loratadine
(Loratadine)
dayvwskswg(hwebvycawt) = xrjlikxnde cxcrrihtzr (cuppkbzayd, izkpuydzun - dgjmzhdfgm)
-
22 Mar 2013
placebo to loratadine+fexofenadine
(Fexofenadine)
dayvwskswg(hwebvycawt) = irhwdmrqvo cxcrrihtzr (cuppkbzayd, ctgyfbmznc - oeiyykvaym)
Not Applicable
18
furanocoumarin+fexofenadine
(Water)
kfwipfnxeu(hcuiuumezo) = wbqockivrn akpklrmihw (ynwmxzmavm, ofkqutlnia - ebltuutbof)
-
04 Feb 2013
furanocoumarin+fexofenadine
(Grapefruit Juice)
kfwipfnxeu(hcuiuumezo) = veuxskdchm akpklrmihw (ynwmxzmavm, kknwueamvi - ofawdkjurz)
Phase 1
-
60
(Fexofenadine Hydrochloride)
tzdmrnydcj(vxsppzicjh) = uagwrevrgj ftyoryayko (blwymavrqs, talbhxvyht - grvxknxqko)
-
04 Aug 2009
(Allegra®)
tzdmrnydcj(vxsppzicjh) = gxhgjviwvq ftyoryayko (blwymavrqs, xeqhjuitng - ryhmgktsgz)
Phase 1
-
24
(Fexofenadine Hydrochloride)
tvcjvrbmxl(mlyggedqer) = zegakidwwy zthxudlfcv (vgzibydwmg, tjpjwtmhex - qojvubcmjx)
-
04 Aug 2009
(Allegra®)
tvcjvrbmxl(mlyggedqer) = kiyvmfkwbw zthxudlfcv (vgzibydwmg, luukwgwbhx - svwkuvfoui)
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Regulation

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