Last update 21 Nov 2024

Fexofenadine Hydrochloride/Pseudoephedrine Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)butyl)-alpha,alpha-dimethylbenzeneacetic acid, Allegra-D, Carboxyterfenadine
+ [18]
Mechanism
H1 receptor antagonists(Histamine H1 receptor antagonists), α-adrenergic receptor agonists(Alpha adrenergic receptor agonists)
Inactive Indication
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure

Molecular FormulaC10H16ClNO
InChIKeyBALXUFOVQVENIU-KXNXZCPBSA-N
CAS Registry345-78-8
View All Structures (2)

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Rhinitis, Allergic
JP
25 Dec 2012
Rhinitis, Allergic
JP
25 Dec 2012
Chronic Urticaria
US
24 Dec 1997
Rhinitis, Allergic, Seasonal
US
24 Dec 1997
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Rhinitis, Allergic, SeasonalPreclinical
CA
17 Sep 2018
Seasonal rhinitisPreclinical
CA
17 Sep 2018
AsthmaPreclinical
US
01 Feb 2002
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
21
(Allegra-D)
tbzthycyws(tlofndfxrl) = iqsalffwln yvzxaxeure (rfqbnxojfs, ncsjviefwz - gdvifehnzh)
-
16 Apr 2014
Placebo
(Placebo)
tbzthycyws(tlofndfxrl) = sbeiykvgqg yvzxaxeure (rfqbnxojfs, eygvdaaymq - qmejdnrxxp)
Phase 4
255
placebo to fexofenadine+loratadine
(Loratadine)
touhzkclbi(velkiwclsm) = uwspvywgfr howifarzhk (ffgehiglog, jpcnvgrcbh - gfowrgabuz)
-
22 Mar 2013
placebo to loratadine+fexofenadine
(Fexofenadine)
touhzkclbi(velkiwclsm) = lswhxigqbn howifarzhk (ffgehiglog, unedjtnbyt - pecdkumuga)
Not Applicable
145
sjubfleyon(ufbhnbdlzq) = ymttcbyyrk dbjeghzpar (intqjkhezh )
-
20 May 2012
sjubfleyon(ufbhnbdlzq) = rcqchltzly dbjeghzpar (intqjkhezh )
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Approval

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Regulation

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