Last update 21 Jun 2024

Centhaquine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Centhaquine Citrate, PMZ-2010, Lyfaquin
Mechanism
ADRA2B agonists(Alpha-2b adrenergic receptor agonists), α2A-AR agonists(Alpha-2a adrenergic receptor agonists)
Inactive Indication
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
IN (14 May 2020),
Regulation-
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Structure

Molecular FormulaC22H25N3
InChIKeyUJNWGFBJUHIJKK-UHFFFAOYSA-N
CAS Registry57961-90-7

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Shock, Hemorrhagic
IN
14 May 2020
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HemorrhagePhase 2
IN
29 May 2017
ShockPhase 2
IN
29 May 2017
COVID-19Phase 2--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
105
zfumbekcub(pvjbjauokr) = ublrnhlvhn syqbkrarac (pxvbjoxsng )
Positive
01 Jun 2021
Placebo
kmskejbfiq(tuwhtrbskj) = dloejndjef awvfewvmps (jnpsegrfac )
Phase 3
Shock
Adjuvant
197
bjfoxsfkfj(cvowmnzfxi): odds ratio = 4.4 (95% CI, 0.9651 - 23.74), P-Value = 0.037
Positive
05 Nov 2020
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Clinical Trial

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Approval

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Regulation

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