Last update 26 Nov 2024

Pasifolate Exatecan

Overview

Basic Info

Drug Type
Small molecule-drug conjugates
Synonyms
ELU 001, ELU-001, ELU001
Mechanism
FOLR1 antagonists(Folate receptor alpha antagonists), TOP1 inhibitors(DNA topoisomerase I inhibitors)
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
endometrial clear cell carcinomaPhase 2
US
13 Sep 2021
Endometrioid CarcinomaPhase 2
US
13 Sep 2021
Fallopian Tube CarcinomaPhase 2
US
13 Sep 2021
Krukenberg TumorPhase 2
US
13 Sep 2021
Ovarian adenocarcinomaPhase 2
US
13 Sep 2021
Ovarian Serous AdenocarcinomaPhase 2
US
13 Sep 2021
Peritoneal NeoplasmsPhase 2
US
13 Sep 2021
Recurrent Endometrial CancerPhase 2
US
13 Sep 2021
Recurrent ovarian cancerPhase 2
US
13 Sep 2021
Uterine CarcinosarcomaPhase 2
US
13 Sep 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
Solid tumor
FRα overexpression
40
mbjainyjdm(ruulbiblow) = cbantratii jcbalvoadz (mmypirztxi )
Positive
23 Oct 2023
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Clinical Trial

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Approval

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Regulation

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