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Last update 25 Oct 2025
Inezetamab
Last update 25 Oct 2025
Overview
Basic Info
Drug Type Bispecific antibody |
Synonyms AMG-994 |
Target |
Action agonists, inhibitors |
Mechanism CD40 agonists(Tumor necrosis factor receptor superfamily member 5 agonists), MSLN inhibitors(Mesothelin inhibitors) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
License Organization- |
Drug Highest PhasePendingPhase 1 |
First Approval Date- |
Regulation- |
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Structure/Sequence
Sequence Code 669330456
Source: *****
Sequence Code 669332144
Source: *****
Related
1
Clinical Trials associated with InezetamabNCT04727554
A Phase 1, Multicenter, Open-label, Dose Exploration and Dose Expansion Study Evaluating the Safety, Tolerability, Pharmacokinetics and Efficacy of AMG 994 Monotherapy and Combination of AMG 994 and AMG 404 in Subjects With Advanced Solid Tumors
100 Clinical Results associated with Inezetamab
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100 Translational Medicine associated with Inezetamab
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100 Patents (Medical) associated with Inezetamab
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100 Deals associated with Inezetamab
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Locally Advanced Malignant Solid Neoplasm | Phase 1 | United States | 29 Apr 2021 | |
| Locally Advanced Malignant Solid Neoplasm | Phase 1 | Japan | 29 Apr 2021 | |
| Locally Advanced Malignant Solid Neoplasm | Phase 1 | Australia | 29 Apr 2021 | |
| Locally Advanced Malignant Solid Neoplasm | Phase 1 | Belgium | 29 Apr 2021 | |
| Locally Advanced Malignant Solid Neoplasm | Phase 1 | Canada | 29 Apr 2021 | |
| Locally Advanced Malignant Solid Neoplasm | Phase 1 | France | 29 Apr 2021 | |
| Locally Advanced Malignant Solid Neoplasm | Phase 1 | Germany | 29 Apr 2021 | |
| Locally Advanced Malignant Solid Neoplasm | Phase 1 | Poland | 29 Apr 2021 | |
| Locally Advanced Malignant Solid Neoplasm | Phase 1 | Spain | 29 Apr 2021 | |
| Locally Advanced Malignant Solid Neoplasm | Phase 1 | United Kingdom | 29 Apr 2021 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
Phase 1 | 11 | rgxnibcuix = ttivhmazcr ytlrsogins (ctqwytemde, ocahabjocf - iygxombrua) View more | - | 06 Jan 2025 | |||
rgxnibcuix = bqxrxdoxlv ytlrsogins (ctqwytemde, zvkncgcjyx - cawbphbrvk) |
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Translational Medicine
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Biosimilar
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Regulation
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