Last update 21 Nov 2024

Caffeine/Propranolol

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target
A1R x A2aR x β-adrenoceptors
Mechanism
A1R antagonists(Adenosine A1 receptor antagonists), A2aR antagonists(Adenosine A2a receptor antagonists), β-adrenoceptors antagonists(Beta adrenergic receptors antagonists)
Therapeutic Areas
Other Diseases
Active Indication
Stress Disorders, Post-Traumatic
Inactive Indication
Migraine Disorders
Originator Organization-
Active Organization
Otsuka Pharmaceutical Development & Commercialization, Inc.
Inactive Organization
Stanford UniversityStanford University
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Structure

Molecular FormulaC8H10N4O2
InChIKeyRYYVLZVUVIJVGH-UHFFFAOYSA-N
CAS Registry58-08-2
View All Structures (2)

Related

1
Clinical Trials associated with Caffeine/Propranolol
NCT01080677 / CompletedPhase 2IIT
Randomized Double-Blind Study to Evaluate the Dose-Related Efficacy and Safety of Caffeine/Propranolol in the Treatment of Acute Migraine
100 Clinical Results associated with Caffeine/Propranolol
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100 Translational Medicine associated with Caffeine/Propranolol
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100 Patents (Medical) associated with Caffeine/Propranolol
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100 Deals associated with Caffeine/Propranolol
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Migraine DisordersPhase 2
US
Stanford UniversityStanford University
14 Feb 2017
Stress Disorders, Post-TraumaticPhase 1
US
Otsuka Pharmaceutical Development & Commercialization, Inc.
24 Jan 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
NCT01080677 (CTgov)
Phase 2
Acute migraine
60
placebo
(Placebo)
crxcsyncex(fmlovjrhti) = fnpsclilrw ucidcotiad (ikafbolinx, mjodivxxdg - qwgxrmeqyj)
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-
24 Feb 2017
(Low Dose)
crxcsyncex(fmlovjrhti) = gdpgtjyxbr ucidcotiad (ikafbolinx, btfurxmdeh - bigeqyayeo)
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Approval

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Regulation

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