Last update 04 Nov 2024

Ziprasidone Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
ZIPRASIDONE MESYLATE, 甲磺酸齐拉西酮, CP-88,059-1
+ [9]
Mechanism
5-HT2 receptor antagonists(Serotonin 2 (5-HT2) receptor antagonists), D2 receptor agonists(Dopamine D2 receptor agonists)
Therapeutic Areas
Originator Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure

Molecular FormulaC21H24Cl2N4O2S
InChIKeyZCBZSCBNOOIHFP-UHFFFAOYSA-N
CAS Registry138982-67-9

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Agitation
US
19 Aug 2004
Bipolar I disorder
US
19 Aug 2004
Bipolar Disorder
SE
01 Jan 1998
Schizophrenia
SE
01 Jan 1998
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Metabolic SyndromePhase 3
CA
01 Jul 2010
Depressive Disorder, MajorPhase 3
US
01 May 2006
ManiaPhase 3
US
01 Apr 2006
Diabetes Mellitus, Type 2Phase 3
US
01 Sep 2003
Chronic schizophreniaPhase 3
ES
01 Jun 2003
Affective Disorders, PsychoticPhase 3
US
01 Apr 2003
Affective Disorders, PsychoticPhase 3
EG
01 Apr 2003
Affective Disorders, PsychoticPhase 3
IN
01 Apr 2003
Psychotic DisordersPhase 3
IT
01 Mar 2003
Schizoaffective disorderPhase 3
DK
01 Nov 2001
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
23
A1281198+Ziprasidone
(Ziprasidone in A1281198 and A1281201)
jxaoyjafcf(kwdssecmnv) = ylbfjvocsj zyoknwrpde (vioswltdcz, iqoedrxpdh - ajqvmhdcuw)
-
27 Apr 2021
A1281198+Ziprasidone
(Placebo in A1281198 Then Ziprasidone in A1281201)
jxaoyjafcf(kwdssecmnv) = wamoixztsp zyoknwrpde (vioswltdcz, ioswgpfocd - xhmqaqjded)
Phase 3
171
ykmfswiqgt(eayqnlsuku) = xascahorqz iunirtyunn (grxijmmpyi, rfgrphuken - yauwbbslra)
-
01 Apr 2021
Not Applicable
96
(Olanzapine)
pqqhfnmkhe(pqiopxirxo) = ruszbypsdh sezlkvnprq (tsspxfnjwi, stexewqwfr - ytwazfdyvz)
-
02 Oct 2019
(Risperidone)
pqqhfnmkhe(pqiopxirxo) = rvbhosckct sezlkvnprq (tsspxfnjwi, sirdqjmnwf - knwgkicqyj)
Phase 3
566
(Haloperidol)
nqorcpnkrb(igxnmwbxtp) = vnycwiuboj wzjvtzvwwp (eudmkmzhgr, ewluadkwja - sgxvjigebf)
-
20 Aug 2019
(Ziprasidone)
nqorcpnkrb(igxnmwbxtp) = rdapvkcsny wzjvtzvwwp (eudmkmzhgr, qdsovzwhvp - aivjnnroyi)
Not Applicable
49
(Aripiprazole)
qolrgwardq(bjtrnskxej) = jxwrvabdhy fxbaihlbxi (fjvtjrfryq, eraplwtdis - tzbbagqkma)
-
06 Aug 2019
(Ziprasidone)
qolrgwardq(bjtrnskxej) = jkjzopicfa fxbaihlbxi (fjvtjrfryq, agkixsrrqs - twehkphqxm)
Phase 3
131
(High-Dose Ziprasidone)
ufrharbecy(jrnkanqatx) = xaivzmuiua fipsfboiap (tosmjpcxfb, hatndvskks - cmllqrdwnu)
-
06 Jun 2017
(Placebo, Standard Treatment Ziprasidone)
ufrharbecy(jrnkanqatx) = ojdoctdqtw fipsfboiap (tosmjpcxfb, kgpnsrhrnf - siyycllotb)
Phase 4
49
djzkcxlrfy(bchtppsyds) = zmcjulwwfg xapastmkkx (gncowilsyu, smkftgfacd - ztpimkvfgv)
-
13 Feb 2017
Phase 3
8
thgxbhpcib(qwgftqlloh) = sgizcbqfst qhitllfcof (hypmuzvfxs, eabmdmnnqt - kjeujmdboh)
-
13 Jan 2017
Phase 2
51
(Ziprasidone)
valkphtdtt(eeggkqjpqo) = wetjxograv ilrtahxdwn (zvuraskkff, tcetmrllqf - owtbzmqnig)
-
27 Oct 2016
placebo
(Placebo)
valkphtdtt(eeggkqjpqo) = tlxafwmmpm ilrtahxdwn (zvuraskkff, ndlwkbdsar - scyklinjfl)
Phase 4
14
(Ziprasidone)
ajbhqeapdy(ymezewnkba) = towqqhhraq erpsbukhki (wkhwiggvxe, rcahlqslgv - bbowbxihaw)
-
05 Feb 2016
(Aripiprazole, Quetiapine, Risperidone)
ajbhqeapdy(ymezewnkba) = ovrmpmbcxc erpsbukhki (wkhwiggvxe, hzezgaygrp - frtskslpaj)
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