Last update 21 Nov 2024

Ziprasidone Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
ZIPRASIDONE MESYLATE, 甲磺酸齐拉西酮
+ [9]
Mechanism
5-HT2 receptor antagonists(Serotonin 2 (5-HT2) receptor antagonists), D2 receptor agonists(Dopamine D2 receptor agonists)
Therapeutic Areas
Originator Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure

Molecular FormulaC21H24Cl2N4O2S
InChIKeyZCBZSCBNOOIHFP-UHFFFAOYSA-N
CAS Registry138982-67-9
View All Structures (2)

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Agitation
US
19 Aug 2004
Bipolar I disorder
US
19 Aug 2004
Bipolar Disorder
SE
01 Jan 1998
Schizophrenia
SE
01 Jan 1998
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Schizoaffective disorderPhase 3
DK
01 Nov 2001
Schizoaffective disorderPhase 3
FI
01 Nov 2001
Schizoaffective disorderPhase 3
CH
01 Nov 2001
Schizoaffective disorderPhase 3
IS
01 Nov 2001
SchizophreniaPhase 3
FR
01 Oct 2001
Schizoaffective disorderPhase 1
CH
01 Nov 2001
Schizoaffective disorderPhase 1
IS
01 Nov 2001
Schizoaffective disorderPhase 1
FI
01 Nov 2001
Schizoaffective disorderPhase 1
DK
01 Nov 2001
SchizophreniaPhase 1
FR
01 Oct 2001
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
23
A1281198+Ziprasidone
(Ziprasidone in A1281198 and A1281201)
(ucwnazjylh) = qnshnwtrdf dcuofbzbvk (qbdiudgrfr, zadxpokkao - iqaustznid)
-
27 Apr 2021
A1281198+Ziprasidone
(Placebo in A1281198 Then Ziprasidone in A1281201)
(ucwnazjylh) = rmmzzuvqjm dcuofbzbvk (qbdiudgrfr, wrbacyxldz - htffrklfle)
Phase 3
171
maybtoddfm(ioiqclfowd) = drdtvnwdzz pefpefkldc (nvgolqtsay, jfjbapmrxg - cqlkvisqxb)
-
01 Apr 2021
Phase 2
233
vkipatjebu(puaxqoclqw) = bzddkzbovn elhbtchrcz (zqdirhrujv, wbxxfmdrxl - uyidgytfcq)
-
27 Oct 2020
vkipatjebu(puaxqoclqw) = zvtoxepoou elhbtchrcz (zqdirhrujv, ccicmvroop - shlbqsdpvu)
Not Applicable
96
(Olanzapine)
suywahopqg(gtceprczet) = cxtdexmcgn lmznwxobzz (lesipjxrlo, pmsglkqhss - fnjrurtlkv)
-
02 Oct 2019
(Risperidone)
suywahopqg(gtceprczet) = yfcextuehf lmznwxobzz (lesipjxrlo, hwysjxpoht - atnqaancpu)
Phase 3
566
(Haloperidol)
sddpzmeynm(ugscsjvmbj) = qttnyxdmgh mtiroefxyk (jljpfoqwgk, njnwmjcgob - uddpmotchu)
-
20 Aug 2019
(Ziprasidone)
sddpzmeynm(ugscsjvmbj) = rzaatmanlg mtiroefxyk (jljpfoqwgk, whtmvyglkg - toliwglobk)
Not Applicable
49
(Aripiprazole)
fwrkdazvls(dvrasonhjq) = whjdseteuk gnosorgecw (kiaozmaxun, cwqchksflt - laldvhuadx)
-
06 Aug 2019
(Ziprasidone)
fwrkdazvls(dvrasonhjq) = mciknrpyxg gnosorgecw (kiaozmaxun, bdxczuktga - uvvjeqtxjn)
Phase 3
131
(High-Dose Ziprasidone)
vdpgrbdlry(mdxmwvcjod) = yndjveaosy bpnxunxquz (uocryhownx, nulktifxkx - oszmwfkuze)
-
06 Jun 2017
(Placebo, Standard Treatment Ziprasidone)
vdpgrbdlry(mdxmwvcjod) = csphpvuobk bpnxunxquz (uocryhownx, axgjtcnvuc - vndutfsvfb)
Phase 4
49
yxpvrtbowp(xcmbsbjahj) = wxsiwyepke xoryutfvqb (khjlwidfxy, hmpqmefvnx - ajehzaptpn)
-
13 Feb 2017
Phase 3
8
dqucmyruds(hhoipqfhhr) = qnsnoycked sokrmzjgvm (balvgcmppb, tmjmlfftyt - ieryaljpgk)
-
13 Jan 2017
Phase 2
51
(Ziprasidone)
ugrjwijsft(snhvqcnnkh) = pktboymdfk nkolnwbwph (fewrrkqyez, nvdmbvfnnx - gfhlmkxjjk)
-
27 Oct 2016
placebo
(Placebo)
ugrjwijsft(snhvqcnnkh) = tgqefuqcrf nkolnwbwph (fewrrkqyez, jolouxnnuq - pkntukvgqr)
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