Last update 13 Feb 2025

CAN-1012

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
CAN 1012, CAN-1012, CAN007
Target
TLR7
Mechanism
TLR7 agonists(Toll like receptor 7 agonists)
Therapeutic Areas
Neoplasms
Active Indication
Advanced Malignant Solid NeoplasmLocally Advanced Malignant Solid NeoplasmNeoplasm Metastasis
Inactive Indication-
Originator Organization
Conway (Guangzhou) Biotechnology Co., Ltd.Conway (Guangzhou) Biotechnology Co., Ltd.
Active Organization
Conway (Guangzhou) Biotechnology Co., Ltd.Conway (Guangzhou) Biotechnology Co., Ltd.IriSys, Inc.
Inactive Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
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Related

5
Clinical Trials associated with CAN-1012
NCT06410703
/ RecruitingPhase 1/2
A Phase Ib/IIa, Dose Escalation, Open-Label Study of Intratumoral CAN1012 Combined With PD-1 in Patients With Unresectable or Metastatic Advanced Solid Tumors
CTR20241555
/ RecruitingPhase 1/2
瘤内注射CAN1012注射液联合特瑞普利单抗在晚期实体瘤患者中的安全性、耐受性及初步有效性的Ib/IIa 期临床试验
[Translation] Phase Ib/IIa clinical trial to evaluate the safety, tolerability and preliminary efficacy of intratumoral CAN1012 injection combined with toripalimab in patients with advanced solid tumors
NCT05580991
/ Active, not recruitingPhase 1
A Phase 1, Dose Escalation, Open-Label Study of Intratumoral CAN1012 in Subjects With Unresectable or Metastatic Advanced Solid Tumors
100 Clinical Results associated with CAN-1012
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100 Translational Medicine associated with CAN-1012
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100 Patents (Medical) associated with CAN-1012
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100 Deals associated with CAN-1012
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 2
CN
Conway (Guangzhou) Biotechnology Co., Ltd.Conway (Guangzhou) Biotechnology Co., Ltd.
18 Jun 2024
Locally Advanced Malignant Solid NeoplasmPhase 1
CN
Conway (Guangzhou) Biotechnology Co., Ltd.Conway (Guangzhou) Biotechnology Co., Ltd.
09 Sep 2022
Neoplasm MetastasisPhase 1
US
Conway (Guangzhou) Biotechnology Co., Ltd.Conway (Guangzhou) Biotechnology Co., Ltd.
20 Jan 2022
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Clinical Result

Indication
Phase
Evaluation
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Approval

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Regulation

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