Last update 20 Jun 2024

Thiostrepton

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
RSO-021
Mechanism
50S subunit inhibitors(50S ribosomal subunit inhibitors), PRDX3 inhibitors(peroxiredoxin 3 inhibitors)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
RegulationOrphan Drug (EU)

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Malignant Pleural EffusionPhase 2
GB
31 Mar 2022
Malignant Pleural EffusionPhase 2
GB
31 Mar 2022
Malignant Pleural MesotheliomaPhase 2
GB
31 Mar 2022
Metastatic breast cancerPhase 2
GB
-
Non-Small Cell Lung CancerPhase 2
GB
-
Ovarian CancerPhase 2
GB
-
Adenocarcinoma of LungPhase 1
GB
30 Jan 2022
Peritoneal NeoplasmsPreclinical
GB
30 Jan 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
PRX3
15
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Positive
24 May 2024
lafbuioiuz(syiihealju) = sibrbuuwdn xqepnvkify (uzmhummeaj )
Phase 2
168
gxgicvaunb(wnbsxwdmlq) = Pre- and post-dose primary prophylaxis for local inflammatory reactions to intrapleural injection was instituted during dose escalation, using corticosteroids, NSAIDS and paracetamol aeavtkmefq (edxjgbjwqb )
Positive
24 May 2024
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Clinical Trial

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Approval

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Regulation

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