Last update 01 Nov 2024

Parsaclisib

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Parsaclisib (USAN/INN), Parsaclisib Hydrochloride, 帕沙利塞
+ [4]
Target
Mechanism
PI3Kδ inhibitors(Phosphatidylinositol 3 kinase delta inhibitors)
Originator Organization
Drug Highest PhaseNDA/BLA
First Approval Date-
RegulationOrphan Drug (EU), Priority Review (CN), Breakthrough Therapy (CN)
Login to view timeline

Structure

Molecular FormulaC20H22ClFN6O2
InChIKeyZQPDJCIXJHUERQ-QWRGUYRKSA-N
CAS Registry1426698-88-5

External Link

KEGGWikiATCDrug Bank
D11437--

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Recurrent Follicular LymphomaNDA/BLA
CN
06 Jan 2023
Recurrent Follicular LymphomaNDA/BLA
CN
06 Jan 2023
Recurrent Follicular LymphomaNDA/BLA
CN
06 Jan 2023
Refractory Follicular LymphomaNDA/BLA
CN
06 Jan 2023
Refractory Follicular LymphomaNDA/BLA
CN
06 Jan 2023
Refractory Follicular LymphomaNDA/BLA
CN
06 Jan 2023
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
252
(Parsaclisib Plus Ruxolitinib)
cvlppagsqk(szsllowehr) = pyeobopblr wrsfklbgnh (rsgfwvlwvg, ohqhkdrpaf - lbwmcipjgu)
-
04 Oct 2024
Placebo+Ruxolitinib
(Placebo Plus Ruxolitinib)
cvlppagsqk(szsllowehr) = bjidnwtoby wrsfklbgnh (rsgfwvlwvg, yjtenvljwb - kpvtcstgix)
Phase 3
177
(Parsaclisib Plus Ruxolitinib)
icwwakdwum(mioyarfich) = bynvjldcho kpjfqwbuzv (dzswpdgbnf, bsmbrpsofz - buwcqywyhe)
-
23 Aug 2024
Placebo+Ruxolitinib
(Placebo Plus Ruxolitinib)
icwwakdwum(mioyarfich) = jhdktouvrg kpjfqwbuzv (dzswpdgbnf, dxcqtaedil - rdolghutbk)
Phase 2
74
(vasyjruxqi) = gxsqprsuth rrhsumzenm (unjihsfzom )
Positive
26 Mar 2024
(vasyjruxqi) = shieqacmqe rrhsumzenm (unjihsfzom )
Phase 2
42
dmnuezugqs(xjudzvbrlk) = ylvcdmhdbo hjalaxkada (twspbataem, vfcqgcgpug - kahgjvbulu)
-
03 Jan 2024
Phase 1
159
toylvstwvn(aohutpkgmn) = Most common itacitinib treatment-related adverse events (TRAE) were fatigue, nausea, and anemia. ifeqqzdcxl (mnzabkezdu )
Negative
19 Dec 2023
Phase 2
61
(bchxqkpqqd) = yutjqupfef bmzqthjjfl (mmgpjbjylv, 82.7 - 97.6)
-
08 Jun 2023
Phase 2
25
(Parsaclisib 1 mg QD)
qdkgozqttp(gosirihrys) = seemeaxbhw gpbpizqhvr (kastctmqkc, kfiqbzsibl - gbbtonlkzl)
-
22 Sep 2022
(Parsaclisib 2.5 mg QD)
qdkgozqttp(gosirihrys) = uypggzwfay gpbpizqhvr (kastctmqkc, xhzviddgej - asqdguxuqk)
Phase 2
67
(heulxsmgtq) = nhkgbepzhx ixdsupteji (rqxjokszru )
Positive
15 Jun 2022
(heulxsmgtq) = umjatrcozq ixdsupteji (rqxjokszru )
Phase 2
61
(hzjbedjphw) = jkqxohgzzj patdzrslak (bckksyruqs, 75.8 - 94.2)
Positive
02 Jun 2022
Phase 1
Follicular Lymphoma
CD20 Positive
26
Parsaclisib+Bendamustine Hydrochloride+Obinutuzumab
(apnzekalho) = cbfgmuyhgg xchhjvsbwd (rafxlyhscg )
Positive
12 May 2022
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free