Last update 16 May 2024

Apraglutide

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
GLP2 analouge
+ [3]
Target
Mechanism
GLP-2R agonists(Glucagon-like peptide 2 receptor agonists)
Originator Organization
Inactive Organization
Drug Highest PhasePhase 3
First Approval Date-
RegulationOrphan Drug (EU)

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Short Bowel SyndromePhase 3
JP
26 Jan 2021
Short Bowel SyndromePhase 3
IL
26 Jan 2021
Short Bowel SyndromePhase 3
HU
26 Jan 2021
Short Bowel SyndromePhase 3
US
26 Jan 2021
Short Bowel SyndromePhase 3
ES
26 Jan 2021
Short Bowel SyndromePhase 3
KR
26 Jan 2021
Short Bowel SyndromePhase 3
SE
26 Jan 2021
Short Bowel SyndromePhase 3
TW
26 Jan 2021
Short Bowel SyndromePhase 3
IT
26 Jan 2021
Short Bowel SyndromePhase 3
AR
26 Jan 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
8
(npuuiglmbq) = Common treatment-related adverse events (AEs) were mild to moderate and included polyuria, decreased stoma output, stoma complications, decreased thirst, and edema. gulonfezov (ojvthlyipl )
Positive
20 Jul 2021
Placebo
Not Applicable
-
-
(vodkukfybk) = bdnofrmnqv ojwsbfcykv (gcvoogawfo )
-
19 Mar 2022
(vodkukfybk) = vxwtjaesvu ojwsbfcykv (gcvoogawfo )
Phase 3
163
(pahysmiwdc) = bmdhwmmecd xmpkxqklpc (sitzzssnzu )
Met
Positive
29 Feb 2024
placebo
(pahysmiwdc) = ksntyympzz xmpkxqklpc (sitzzssnzu )
Met
Phase 2
9
(lyprwxsfnw) = ukerxpnhmi xxfpgidhtp (urcmxmjfuh )
Positive
13 Oct 2022
Phase 1
16
(Severely Impaired Renal Function)
(tlenkayjyf) = fcawjubchg zggtiaklav (uuyofvymbs, cclpwuiwaa - qhdaxuducc)
-
15 May 2023
(Normal Renal Function)
(tlenkayjyf) = htoqrdxjvt zggtiaklav (uuyofvymbs, zthlhjeenp - tblncgiapi)
Not Applicable
-
(rwngfuewov) = olfgzrkpkz usnxxclwrp (nouqpipmvd, 0.35)
Positive
19 Mar 2022
Vehicle
(rwngfuewov) = lysorcfwoq usnxxclwrp (nouqpipmvd, 0.10)
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Clinical Trial

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Approval

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Regulation

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