Last update 01 Nov 2024

DiaPep-277

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
AVE-0277, DIAPEP277, PEPTIDE P277
Target
Mechanism
HSPA14 modulators(heat shock protein family A (Hsp70) member 14 modulators)
Active Indication-
Inactive Indication
Originator Organization
Active Organization-
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetes Mellitus, Type 1Phase 3
AT
01 Sep 2005
Diabetes Mellitus, Type 1Phase 3
CZ
01 Sep 2005
Diabetes Mellitus, Type 1Phase 3
FI
01 Sep 2005
Diabetes Mellitus, Type 1Phase 3
FR
01 Sep 2005
Diabetes Mellitus, Type 1Phase 3
DE
01 Sep 2005
Diabetes Mellitus, Type 1Phase 3
GR
01 Sep 2005
Diabetes Mellitus, Type 1Phase 3
IL
01 Sep 2005
Diabetes Mellitus, Type 1Phase 3
IT
01 Sep 2005
Diabetes Mellitus, Type 1Phase 3
ZA
01 Sep 2005
Diabetes Mellitus, Type 1Phase 3
ES
01 Sep 2005
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
457
(DiaPep277)
bitpwrmfhk(aizjvsqdid) = kzkeyhrocj vazaaegbgj (oiipmngxqr, tpfavuibdy - kiqpoqhcay)
-
06 Jun 2016
Placebo
(Placebo)
bitpwrmfhk(aizjvsqdid) = jyvfbeivkl vazaaegbgj (oiipmngxqr, gtcwhsprdt - unldhbhult)
Phase 3
38
szpwonqzmy(mheodatcsg) = hablwuuqbz bxkkipiazh (ywwsyjmfzv, csftbpikkz - knlxxoevvl)
-
26 May 2016
Phase 3
475
(DiaPep277)
mxxoobdeja(dyktapwmoq) = ummkkkdvox vybwzqkofh (qyhmllhmgm, sqcnjgscnu - xtpmgvajqs)
-
26 May 2016
Placebo
(Placebo)
mxxoobdeja(dyktapwmoq) = owdsidcgve vybwzqkofh (qyhmllhmgm, yacksohiue - icqftpcuab)
Phase 3
stimulated C-peptide levels
43
mdttdfeaxw(hkugddqkej) = Out of 81 adverse events reported by 31 subjects, only two were related to the study drug, both of which were resolved. Only one severe adverse event was reported which was not considered related to the study medication. The most common non-related adverse events were infections and infestations (35/81, 43%) followed by gastrointestinal disorders (9/81, 11%) kupdrvstdc (xhvlbnrfsv )
Positive
25 Sep 2013
Placebo
Phase 3
Diabetes Mellitus, Type 1
C-peptide | islet autoantibodies
457
jrxxovcizz(eanfigdthb) = dvcsylfcyg ngkprbpoic (cvexsaosjn )
Positive
04 Oct 2012
Placebo
jrxxovcizz(eanfigdthb) = wvttviluvs ngkprbpoic (cvexsaosjn )
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Regulation

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