Last update 24 May 2025

Ravoxertinib

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Ravoxertinib (USAN/INN), GD0 994, GDC-0994
+ [1]
Target
Action
inhibitors
Mechanism
ERK inhibitors(ERK subfamily inhibitors)
Originator Organization
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC21H18ClFN6O2
InChIKeyRZUOCXOYPYGSKL-GOSISDBHSA-N
CAS Registry1453848-26-4

External Link

KEGGWikiATCDrug Bank
D11285--

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
MelanomaPhase 1
United States
16 Jun 2015
Metastatic Colorectal CarcinomaPhase 1
United States
16 Jun 2015
metastatic non-small cell lung cancerPhase 1
United States
16 Jun 2015
Neoplasm MetastasisPhase 1
United States
16 Jun 2015
Solid tumorPhase 1
United States
06 Apr 2014
Locally Advanced Malignant Solid NeoplasmPhase 1
United States
21 Jun 2013
Locally Advanced Malignant Solid NeoplasmPhase 1
France
21 Jun 2013
Focal Cortical Dysplasia of TaylorPreclinical
China
04 Jun 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
47
qimtfrwxoh(zqaijwpfya) = A single DLT of grade 3 rash occurred at 600 mg pqdsrruxny (sgfebufpsy )
Positive
15 Mar 2020
Phase 1
24
(Not Assigned)
jusgpkfvod = hcczgtrntf gvfxbyenil (euwxgzdtli, pazsomenbw - ofszbtffdf)
-
24 Aug 2018
(COB 20 mg + GDC 200 mg)
jusgpkfvod = knhtqsnrdx gvfxbyenil (euwxgzdtli, tmkiofzenw - uqfnvwwlap)
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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