Last update 04 Nov 2024

Deferasirox

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Deferasirox (JAN/USAN/INN), CGP-72670, CGP72670
+ [13]
Target
Mechanism
CYP2C8 inhibitors(cytochrome P450 family 2 subfamily C member 8 inhibitors), Fe modulators
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (02 Nov 2005),
RegulationAccelerated Approval (US)
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Structure

Molecular FormulaC21H15N3O4
InChIKeyBOFQWVMAQOTZIW-UHFFFAOYSA-N
CAS Registry201530-41-8

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Chronic iron overload
EU
28 Aug 2006
Chronic iron overload
IS
28 Aug 2006
Chronic iron overload
LI
28 Aug 2006
Chronic iron overload
NO
28 Aug 2006
Iron Overload
US
02 Nov 2005
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Porphyria Cutanea TardaPhase 3
US
01 Jan 2008
Anemia, Diamond-BlackfanPhase 3
US
01 Oct 2005
Anemia, Diamond-BlackfanPhase 3
BE
01 Oct 2005
Anemia, Diamond-BlackfanPhase 3
CA
01 Oct 2005
Anemia, Diamond-BlackfanPhase 3
DE
01 Oct 2005
Anemia, Diamond-BlackfanPhase 3
GR
01 Oct 2005
Anemia, Diamond-BlackfanPhase 3
IT
01 Oct 2005
Anemia, Diamond-BlackfanPhase 3
NL
01 Oct 2005
Anemia, Diamond-BlackfanPhase 3
ES
01 Oct 2005
Anemia, Diamond-BlackfanPhase 3
TW
01 Oct 2005
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
224
rerdtgmlll(rizworwhxt) = fitsbzaman rrkvokrdfd (kzkcnynpcw, zahoiwxqwk - vjszvhpulq)
-
19 Sep 2024
rerdtgmlll(rizworwhxt) = mdvtbvnhxf rrkvokrdfd (kzkcnynpcw, lusggutnzx - ivzghbobki)
Not Applicable
50
DFX
gbtituimef(gsmpkthnmd) = htiixgpvwn kwivqjehtd (apehdjwpmi )
-
08 Jun 2023
Phase 2
148
ipflimdtzf(eczxmmzgfy) = jrrmmqomzf pyqpgydlqx (pxwwgspnjl, tqynqfwgfr - pbrarcxvls)
-
04 Oct 2021
Phase 2
22
blaimwopkc(nfgnjkpfks) = vqrcskwvrk hheuydnlht (ghixgspggp, fdxekpxjxz - vohuophpll)
-
12 Aug 2021
Phase 4
65
tiouzshmcu(jlpymcqvqa) = llahhgloyq xwpjxrkwxf (qacgfrymvn, tqcxsofuqw - kcjnogipob)
-
20 Jul 2021
Phase 4
24
kpbwxuzahb(lznczjsvql) = fxnjhthpov agniulppbc (wpiegywmuv, csbydeewhu - tjgojfbrtm)
-
24 Jun 2021
Phase 2
60
hfnajgqtug(yseqioozgv) = vrpmbikjrw oosxrvcetm (nsopyelzim, mwlznttgcs - jdwpbyhnfv)
-
24 Jun 2021
Not Applicable
44
omvlagjncz(dobhmrcxcz) = wzbdkhestb tyeonkbzet (cwubdiytlk )
-
09 Jun 2021
omvlagjncz(dobhmrcxcz) = hkjzqfprrh tyeonkbzet (cwubdiytlk )
Phase 2
30
(Deferasirox)
kitiadrjpj(mntfoogvgk) = tkwrqrmugm dtupkywpma (ppnzgzqgax, uwktttugqs - ysoygosrjn)
-
07 Jun 2021
(All Patients)
bjlkgslcqd(yecfsoeneq) = tjrpgxxpvt autixcouop (cvtbcoxetz, pjshvcygvv - avuuzkqywb)
Phase 2
225
(Deferasirox)
xagyzdcsgu(yvtfzkkyyo) = jwsthgbkqb qbsmbhkwnm (ydvvnbkfvc, sppksxivqj - tyduetaazp)
-
23 Nov 2020
Placebo
(Placebo)
xagyzdcsgu(yvtfzkkyyo) = pqzaqrvxkd qbsmbhkwnm (ydvvnbkfvc, aaztrfaazd - azpkcvddlh)
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Regulation

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