Last update 21 Nov 2024

Esepapogene Zalarnarepvec

Overview

Basic Info

Drug Type
Therapeutic vaccine
Synonyms
TheraT LCMV, TheraT-E7E6(Hookipa)
+ [2]
Mechanism
E7 inhibitors(Protein E7 inhibitors), HPV E6 inhibitors(HPV E6 inhibitors), Immunostimulants
Therapeutic Areas
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Oropharyngeal NeoplasmsPhase 2
US
15 Feb 2021
Uterine Cervical CancerPhase 2
US
15 Feb 2021
Human Papillomavirus InfectionPhase 2
US
11 Dec 2019
Human Papillomavirus-Related Squamous Cell CarcinomaPhase 2
NL
11 Dec 2019
Human Papillomavirus-Related Squamous Cell CarcinomaPhase 2
ES
11 Dec 2019
Human Papillomavirus-Related Squamous Cell CarcinomaPhase 2
US
11 Dec 2019
Recurrent Squamous Cell Carcinoma of the Head and NeckPhase 2
NL
11 Dec 2019
Recurrent Squamous Cell Carcinoma of the Head and NeckPhase 2
ES
11 Dec 2019
Recurrent Squamous Cell Carcinoma of the Head and NeckPhase 2
US
11 Dec 2019
NeoplasmsPhase 2--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
-
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-
15 Jun 2022
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Phase 1
HPV-related carcinoma
HPV16 positive
65
(isbklddzlc) = Preliminary safety, efficacy, and immunogenicity data support IV injection of DL3 (5 × 107 units) every 3 weeks (Q3W) as the RP2D for HB-201 single-vector therapy. RP2D for HB-202/HB-201 will be determined in the very near future. lbvgzdcmqp (qfasyddmgn )
Positive
02 Jun 2022
Phase 1/2
62
(rzuurerpky) = lmlfcymfgi vhxhvtsqie (lntzubxtdm )
Positive
09 Nov 2021
(rzuurerpky) = xrmrysxycz vhxhvtsqie (lntzubxtdm )
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Approval

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Regulation

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