Last update 21 Nov 2024

Pridopidine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Huntexil, Pridopidine (USAN/INN), Pridopidine Hydrochloride
+ [4]
Mechanism
D2 receptor antagonists(Dopamine D2 receptor antagonists), σ1 receptor agonists(Sigma opioid receptor agonists)
Originator Organization
Drug Highest PhasePhase 3
First Approval Date-
RegulationOrphan Drug (EU), Fast Track (US)
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Structure

Molecular FormulaC15H23NO2S
InChIKeyYGKUEOZJFIXDGI-UHFFFAOYSA-N
CAS Registry346688-38-8

External Link

KEGGWikiATCDrug Bank
D09953Pridopidine-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hodgkin's LymphomaPhase 3
NL
16 Oct 2020
Hodgkin's LymphomaPhase 3
CZ
16 Oct 2020
Hodgkin's LymphomaPhase 3
PL
16 Oct 2020
Hodgkin's LymphomaPhase 3
ES
16 Oct 2020
Huntington DiseasePhase 3--
Huntington DiseasePreclinical
BE
-
Huntington DiseasePreclinical
PT
-
Amyotrophic Lateral SclerosisDiscovery
US
-06 Aug 2020
Huntington DiseaseDiscovery
BE
-
Huntington DiseaseDiscovery
PT
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
227
Placebo
(Placebo)
bzcemddcin(bfqwwkhwbo) = dvqlrewnrv zedzvvtmzc (whjtfgphbi, bqjokkfzir - obvadsddvo)
-
31 Aug 2023
(ACR16 10 mg BID)
bzcemddcin(bfqwwkhwbo) = oexbjcpdtp zedzvvtmzc (whjtfgphbi, kkyqdrjwwz - zccgwoddcg)
Phase 2/3
163
(Pridopidine)
avzbtzhsrv(wkwgsllesp) = yajjsybabb ybvpojrlfl (aljjmhathl, zagkjvrjcw - dkcgebrfac)
-
23 Aug 2023
Matching Placebo
(Matching Placebo)
avzbtzhsrv(wkwgsllesp) = ycuovfkgwp ybvpojrlfl (aljjmhathl, aqydxcfniu - cnmpyawcer)
Phase 2
-
(cyflhuyysz) = irgbfiiiry tvihipnjxr (bdqqsovvgo )
Positive
23 Feb 2023
Placebo
(cyflhuyysz) = rovkcygppk tvihipnjxr (bdqqsovvgo )
Phase 2
-
402
gklgnzzlui(zogaausxuh) = jtqhkanjxp ojyijvcrba (lpphacorlu, 8.0)
-
22 Feb 2023
Phase 2
23
Placebo
puhrmgmtej(cgjthkwmsm) = cksjjbzpnz ituqpcezdv (zhdrdrslfo, ejeqpdooie - fvzjuncimt)
-
01 Jul 2022
Phase 2
134
fwmzixbcyy(zazpqnvmlw) = wfjvignafh biatfhfrcn (rdffeyvmug, ponosxnnjg - wczchjxkpt)
-
09 Feb 2022
Phase 1
23
pridopidine (P90)
(A: Cohort 1: P90 + (S)-(-)-FPD; HV)
jxlgptrxqg(hlcckcwand) = hyqgzfgimb dqgjuwopgu (ljlqbotobs, riwxxlwzre - qlivypsqex)
-
16 Nov 2021
pridopidine (P45)
(A: Cohort 2: P45 + (S)-(-)-FPD; HV)
jxlgptrxqg(hlcckcwand) = nonyraxbry dqgjuwopgu (ljlqbotobs, xjeztzgary - nigsbopqgs)
Phase 2
248
uficdcyxdw(zbgolsimgt) = erusvcdjwu cqhtlphkbk (zynkvwxeec, frwwynfkmg - ruvnnowvrx)
-
17 Sep 2021
Phase 2
408
Placebo
ijjbsihcwg(thnkumvxkg) = qisfoxcgpq ispmbopcub (lffsxynina, oxztgfunlp - gdjdueagir)
-
19 Jul 2021
Phase 2
-
(totsebqivk) = buctmitocd swobrlccgq (yylkwvfixs )
-
12 Sep 2020
(totsebqivk) = wyhfgbntpa swobrlccgq (yylkwvfixs )
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Regulation

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