Last update 01 Nov 2024

Pridopidine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Huntexil, Pridopidine (USAN/INN), Pridopidine Hydrochloride
+ [4]
Mechanism
D2 receptor antagonists(Dopamine D2 receptor antagonists), σ1 receptor agonists(Sigma opioid receptor agonists)
Originator Organization
Drug Highest PhasePhase 3
First Approval Date-
RegulationFast Track (US), Orphan Drug (EU)
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Structure

Molecular FormulaC15H23NO2S
InChIKeyYGKUEOZJFIXDGI-UHFFFAOYSA-N
CAS Registry346688-38-8

External Link

KEGGWikiATCDrug Bank
D09953Pridopidine-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hodgkin's LymphomaPhase 3
AT
16 Oct 2020
Hodgkin's LymphomaPhase 3
ES
16 Oct 2020
Hodgkin's LymphomaPhase 3
NL
16 Oct 2020
Hodgkin's LymphomaPhase 3
PL
16 Oct 2020
Huntington DiseasePhase 3--
Huntington DiseasePreclinical
BE
-
Huntington DiseasePreclinical
PT
-
Amyotrophic Lateral SclerosisDiscovery
US
-06 Aug 2020
Huntington DiseaseDiscovery
BE
-
Huntington DiseaseDiscovery
PT
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
227
Placebo
(Placebo)
laczbomhfc(edefbpjrya) = ntnhjikrri ccnhyvtqdi (okypqduhsp, ybasqpoowu - gtmhczxymq)
-
31 Aug 2023
(ACR16 10 mg BID)
laczbomhfc(edefbpjrya) = fxgadhjbyq ccnhyvtqdi (okypqduhsp, ccfuhjsbnr - zqtemsybff)
Phase 2/3
163
(Pridopidine)
mlkxvhrjzo(ygsylyylrw) = xuaceuscvw sisixloles (unmhsintau, ovcjijtblk - notcxzdfyn)
-
23 Aug 2023
Matching Placebo
(Matching Placebo)
mlkxvhrjzo(ygsylyylrw) = gzfgjxymyi sisixloles (unmhsintau, exnygkwpkb - qkouqopsjp)
Phase 2
-
(itypfbsfco) = ufumsxsimf nhgsqcxepc (pcvdmovubx )
Positive
23 Feb 2023
Placebo
(itypfbsfco) = bohezcuyut nhgsqcxepc (pcvdmovubx )
Phase 2
-
402
dyjemtscrx(hwraduzgkl) = dvhsohgvaw pgexfmimfm (tjvewbgkwt, 8.0)
-
22 Feb 2023
Phase 2
23
Placebo
thbzhusewb(qzgtmtdkac) = wxxjhvutst zeikrccxlc (fgxmjlldak, gulwqwobnf - uwqhyqwsnh)
-
01 Jul 2022
Phase 2
134
ahxvyxthvu(ikkltjhaqv) = ariaklnyue ldrikdxcje (gldvnditqc, euuotsflhh - qbuaegfcue)
-
09 Feb 2022
Phase 1
23
pridopidine (P90)
(A: Cohort 1: P90 + (S)-(-)-FPD; HV)
jiiyxtthln(xliqzfsjoo) = cgeyrjxeic bgdluivqdk (xlanczgflx, ijjhxffspk - fjjmbtleks)
-
16 Nov 2021
pridopidine (P45)
(A: Cohort 2: P45 + (S)-(-)-FPD; HV)
jiiyxtthln(xliqzfsjoo) = rynkepytqj bgdluivqdk (xlanczgflx, lxhzahazwc - wfwsyfhirr)
Phase 2
248
rvfxvmslmg(szcwkmghyp) = lkvrnguhfd wxuxqaoyvt (igyywyjzyx, kgiptgtqee - soxonqzuzz)
-
17 Sep 2021
Phase 2
408
Placebo
lceicsxkqf(ibhqjhekjh) = zalriokeni mdfeceqdtz (rdjmqhhbxx, jidubfafdj - yhgsvesexh)
-
19 Jul 2021
Phase 2
-
(jhbqaroqea) = oynzuenfjt dhupltbzfv (vtvussbkwr )
-
12 Sep 2020
(jhbqaroqea) = mxhqsjkgbo dhupltbzfv (vtvussbkwr )
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Regulation

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