Last update 31 May 2025

BMS-986465

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
BMS 986465, BMS986465
Target
TYK2
Action
inhibitors
Mechanism
TYK2 inhibitors(Tyrosine-protein kinase 2 inhibitors)
Therapeutic Areas
Nervous System DiseasesOther Diseases
Active Indication
Neuroinflammation
Inactive Indication-
Originator Organization
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
Active Organization
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with BMS-986465
NCT06144697
/ TerminatedPhase 1
A Phase 1, Randomized, Double-blind, Placebo-controlled, First-in-human, Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Prodrug BMS-986465 and Its Active Derivative, BMS-986464, in Healthy Participants Including Healthy Participants of Japanese Ethnicity and an Open-label Assessment of Food, Formulation, and pH Effects on the Relative Bioavailability of BMS-986465 and BMS-986464
100 Clinical Results associated with BMS-986465
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100 Translational Medicine associated with BMS-986465
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100 Patents (Medical) associated with BMS-986465
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100 Deals associated with BMS-986465
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
NeuroinflammationPhase 1-
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
-
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Clinical Result

Indication
Phase
Evaluation
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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