Last update 20 Mar 2025

Polyethylene glycol 400/propylene glycol

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Lubricant Eye (PG-PEG 400), Systane (propylene glycol) ophthalmic (eye), Systane Gel ophthalmic (eye)
+ [6]
Target-
Action-
Mechanism-
Therapeutic Areas
Active Indication
Originator Organization
Active Organization
Drug Highest PhaseApproved
First Approval Date
China (05 Jan 2016),
Regulation-
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Structure/Sequence

Molecular FormulaC3H8O2
InChIKeyDNIAPMSPPWPWGF-UHFFFAOYSA-N
CAS Registry57-55-6

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Eye Diseases
China
05 Jan 2016
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Dystrophy, MacularPhase 1
Latvia
31 Aug 2010
CataractPreclinical-15 Jan 2021
Functional disorderPreclinical-15 Jan 2021
Meibomian Gland DysfunctionPreclinical-15 Jan 2021
Ocular inflammationPreclinical-15 Jan 2021
Dystrophy, MacularPreclinical
Latvia
31 Aug 2010
Glycogen Storage Disease Type IIPreclinical
Latvia
31 Aug 2010
Kerato conjunctivitis siccaPreclinical
Singapore
31 Jul 2009
BlepharitisPreclinical
Singapore
01 Jul 2009
XerophthalmiaPreclinical
Singapore
01 Jul 2009
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
69
(Systane Balance)
(gjodenqstm) = mhrqfxrqlc asxzuqzfwf (ofmhavmyis, jarnkoubvk - rilhpxfsky)
-
09 Apr 2021
Optive Lubricant Eye Drops
(Optive Lubricant Eye Drops)
(gjodenqstm) = cjvgczjvhu asxzuqzfwf (ofmhavmyis, yagtylzuhn - qxforrvfob)
Phase 3
79
xrdulqhyfg(sdzkppsdse) = ckarbtrnmt eqzywcyxzj (eknbwrifry, ymwmuewkjr - xojleknpqk)
-
04 Jan 2017
xrdulqhyfg(sdzkppsdse) = fhcercesve eqzywcyxzj (eknbwrifry, ogkelnphot - ecmkrcjsun)
Phase 3
30
(Systane Ultra)
ajugdwqhlo(eakerqvsqx) = dsfssizxrt scaqnmpscg (oudjiulkwx, oxhgmyebvf - tkclbynzrf)
-
12 Aug 2011
Refresh eye drops
(Refresh)
ajugdwqhlo(eakerqvsqx) = ysrwmtfvwd scaqnmpscg (oudjiulkwx, zuhmtjonwy - czddzjsrbd)
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Regulation

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