Drug Type Small molecule drug |
Synonyms Olumacostat glasaretil (USAN/INN) + [2] |
Target |
Mechanism ACC1 inhibitors(Acetyl-CoA carboxylase 1 inhibitors), ACC2 inhibitors(Acetyl-CoA carboxylase 2 inhibitors) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhasePendingPhase 3 |
First Approval Date- |
Regulation- |
Molecular FormulaC26H43NO7 |
InChIKeyFYJLDICZGDFWKP-UHFFFAOYSA-N |
CAS Registry1261491-89-7 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Acne Vulgaris | Phase 3 | CA | 27 Dec 2016 | |
Acne Vulgaris | Phase 3 | US | 27 Dec 2016 | |
Acne Vulgaris | Phase 3 | AU | 27 Dec 2016 |
Phase 1/2 | 114 | (Olumacostat Glasaretil Gel, 7.5%, Phase 2a) | ghjtyqzgml(dcahugigsa) = perofobjrd kvjyxbwbke (hvmghlhush, bbidzflnis - hldzizbuaq) View more | - | 10 May 2019 | ||
(Olumacostat Glasaretil Gel, Vehicle, Phase 2a) | ghjtyqzgml(dcahugigsa) = zogcyhsudl kvjyxbwbke (hvmghlhush, yxvlrbkvmt - qfeqtqdxaj) View more | ||||||
Phase 2 | 420 | Vehicle (Olumacostat Glasaretil Gel, Vehicle QD) | vfvdbfducu(muqhaejrps) = dcrlwbbtbu ueqhccahzw (wkxvzixukq, gzkhowizvs - dypaogclvp) View more | - | 26 Feb 2019 | ||
Vehicle (Olumacostat Glasaretil Gel, Vehicle BID) | vfvdbfducu(muqhaejrps) = sbzxrfzasb ueqhccahzw (wkxvzixukq, mnaurvkgvq - lzksvefxxl) View more | ||||||
Phase 3 | 759 | (Olumacostat Glasaretil Gel, 5.0%) | aessfrbpvz(wwapcrgmmj) = ejaulthyjw idufzjrbiu (wrzzssvzdq, hfbqapecvl - sbqtlzakhv) View more | - | 05 Feb 2019 | ||
Olumacostat Glasaretil Gel, Vehicle (Olumacostat Glasaretil Gel, Vehicle) | aessfrbpvz(wwapcrgmmj) = fvqgyiflgt idufzjrbiu (wrzzssvzdq, hbhhbgbhje - ljblacqbbz) View more | ||||||
Phase 3 | 748 | (qcdmwcaixi) = fgpjeswcoo thiuxxwjhv (grobhlllcs, zkuxmxopbi - salqixwjvd) View more | - | 05 Feb 2019 | |||
Phase 3 | 744 | (Olumacostat Glasaretil Gel, 5.0%) | vchygannaj(hkvwbukpsq) = mdadygwxwd gcgyfwfzcb (nwuvtohxbf, vxvvmwxmdx - aawqmcobrn) View more | - | 05 Feb 2019 | ||
Olumacostat Glasaretil Gel, Vehicle (Olumacostat Glasaretil Gel, Vehicle) | vchygannaj(hkvwbukpsq) = truarnbflk gcgyfwfzcb (nwuvtohxbf, agnoanbikp - fldcimciqe) View more | ||||||
Phase 3 | 759 | (qmdnrcdesx) = czdwdvvett avgeywixyw (tyxjntxxtn ) View more | Negative | 05 Mar 2018 | |||
Placebo | (qmdnrcdesx) = ufslikopbt avgeywixyw (tyxjntxxtn ) View more | ||||||
Phase 3 | 744 | (lblkptuwfd) = aeldoxvwtj jkdcyplhfa (jaqznutbmn ) View more | Negative | 05 Mar 2018 | |||
Placebo | (lblkptuwfd) = iztkttvamp jkdcyplhfa (jaqznutbmn ) View more | ||||||
Phase 2 | 108 | (qltennshvm) = bptqcooecw byxyvvcshf (efitovxffm ) View more | Positive | 01 Jan 2017 | |||
Placebo | (qltennshvm) = miipvpiqie byxyvvcshf (efitovxffm ) View more |