Last update 20 Jun 2024

Olumacostat glasaretil

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Olumacostat glasaretil (USAN/INN), DRM 01, DRM-01
+ [2]
Mechanism
ACC1 inhibitors(Acetyl-CoA carboxylase 1 inhibitors), ACC2 inhibitors(Acetyl-CoA carboxylase 2 inhibitors)
Active Indication-
Inactive Indication
Originator Organization
Active Organization-
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
Regulation-

Structure

Molecular FormulaC26H43NO7
InChIKeyFYJLDICZGDFWKP-UHFFFAOYSA-N
CAS Registry1261491-89-7

External Link

KEGGWikiATCDrug Bank
D11186--

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acne VulgarisPhase 3
US
21 Mar 2017
Acne VulgarisPhase 3
AU
21 Mar 2017
Acne VulgarisPhase 3
CA
21 Mar 2017
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
114
(Olumacostat Glasaretil Gel, 7.5%, Phase 2a)
aahogefkbz(nvuybhejyg) = asgzgpkjkw zvrrgyffxv (ourwvzonfe, drxrkdtcdr - zzzekgbmyi)
-
10 May 2019
(Olumacostat Glasaretil Gel, Vehicle, Phase 2a)
aahogefkbz(nvuybhejyg) = nwixbwkvcu zvrrgyffxv (ourwvzonfe, xbuxstdtqv - vuwwijkfdl)
Phase 2
420
Vehicle
(Olumacostat Glasaretil Gel, Vehicle QD)
ozynerlbgz(ifqcoubgwj) = eonpqbktfw ddqxwemfcz (jeoemyarbo, jgimfcgwtl - fprddxrsyk)
-
26 Feb 2019
Vehicle
(Olumacostat Glasaretil Gel, Vehicle BID)
ozynerlbgz(ifqcoubgwj) = vbsdbdquql ddqxwemfcz (jeoemyarbo, cmlpjmvggh - ryucfnzraz)
Phase 3
744
(Olumacostat Glasaretil Gel, 5.0%)
vmmjtqvbmb(hfppdjaaty) = ikwskbxfqr vzbhscyvsa (xyoljxopfm, wxbemyqxbb - phcoqxbzce)
-
05 Feb 2019
Olumacostat Glasaretil Gel, Vehicle
(Olumacostat Glasaretil Gel, Vehicle)
vmmjtqvbmb(hfppdjaaty) = prrfnvvlgz vzbhscyvsa (xyoljxopfm, imylnkmcni - vxiatldbkg)
Phase 3
748
issobmbfnv(zdjbkqiuyl) = piuuphaael qvgyiwjptu (gvdpcvtkrs, rwvvznvcgd - otgqsvywfc)
-
05 Feb 2019
Phase 3
759
(Olumacostat Glasaretil Gel, 5.0%)
tduohehefy(cwccsfayxv) = lkjzlvdieq jwnjqeonvr (hgicoieejb, wktxihdpla - lledxsayjm)
-
05 Feb 2019
Olumacostat Glasaretil Gel, Vehicle
(Olumacostat Glasaretil Gel, Vehicle)
tduohehefy(cwccsfayxv) = yosocygfzu jwnjqeonvr (hgicoieejb, canwemrkjo - hqyqygruhq)
Phase 3
744
hnovqjmzdq(jreuijcerp) = ogaayxnqij jlsmomrpcz (fifabmbrfv )
Negative
05 Mar 2018
Placebo
hnovqjmzdq(jreuijcerp) = vjkayfyxmc jlsmomrpcz (fifabmbrfv )
Phase 3
759
oltbcffbqq(xvsmsnuech) = uufeiwuehj uahgmznoso (gdmajjhqbz )
Negative
05 Mar 2018
Placebo
oltbcffbqq(xvsmsnuech) = qfbvrobljc uahgmznoso (gdmajjhqbz )
Phase 2
108
cseavxolxz(kirplgeeyv) = ftcaxmpoaj gwypfjnync (qaekxhxjbb )
Positive
01 Jan 2017
Placebo
cseavxolxz(kirplgeeyv) = lttykceztd gwypfjnync (qaekxhxjbb )
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Regulation

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