Drug Type Small molecule drug |
Synonyms Olumacostat glasaretil (USAN/INN), DRM 01, DRM-01 + [2] |
Target |
Action inhibitors |
Mechanism ACC1 inhibitors(Acetyl-CoA carboxylase 1 inhibitors), ACC2 inhibitors(Acetyl-CoA carboxylase 2 inhibitors) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
License Organization- |
Drug Highest PhasePendingPhase 3 |
First Approval Date- |
Regulation- |
Molecular FormulaC26H43NO7 |
InChIKeyFYJLDICZGDFWKP-UHFFFAOYSA-N |
CAS Registry1261491-89-7 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Acne Vulgaris | Phase 3 | United States | 27 Dec 2016 | |
Acne Vulgaris | Phase 3 | Australia | 27 Dec 2016 | |
Acne Vulgaris | Phase 3 | Canada | 27 Dec 2016 |
Phase 1/2 | 114 | (Olumacostat Glasaretil Gel, 7.5%, Phase 2a) | tivodjombv(reopdoywqp) = aklaosbgoe cgtsgnjrzn (dfmrjkzgfd, 1.107) View more | - | 10 May 2019 | ||
(Olumacostat Glasaretil Gel, Vehicle, Phase 2a) | tivodjombv(reopdoywqp) = cxetlesqnx cgtsgnjrzn (dfmrjkzgfd, 1.079) View more | ||||||
Phase 2 | 420 | Vehicle (Olumacostat Glasaretil Gel, Vehicle QD) | wouzcdbocf(nplyejmxqu) = qrsynonptg exbswbyvki (lsbjdakqmu, 9.79) View more | - | 26 Feb 2019 | ||
Vehicle (Olumacostat Glasaretil Gel, Vehicle BID) | wouzcdbocf(nplyejmxqu) = legywkwbbi exbswbyvki (lsbjdakqmu, 9.04) View more | ||||||
Phase 3 | 759 | (Olumacostat Glasaretil Gel, 5.0%) | pfyqqlbuhx(tdutsrgwcr) = hqaxunssyk dkmjyhfyfe (vethjqwfye, 14.85) View more | - | 05 Feb 2019 | ||
Olumacostat Glasaretil Gel, Vehicle (Olumacostat Glasaretil Gel, Vehicle) | pfyqqlbuhx(tdutsrgwcr) = xyeaijyscx dkmjyhfyfe (vethjqwfye, 14.54) View more | ||||||
Phase 3 | 748 | ypkxbmukmj = aezsbbzafm vpzpsdyraw (eenaojarxu, cgmqcrvwfl - xxosrwozsk) View more | - | 05 Feb 2019 | |||
Phase 3 | 744 | (Olumacostat Glasaretil Gel, 5.0%) | upsdqhyljs(odfrohqhdv) = hpxxsrtjth nktghqxlve (qpjrhgdsxv, 12.16) View more | - | 05 Feb 2019 | ||
Olumacostat Glasaretil Gel, Vehicle (Olumacostat Glasaretil Gel, Vehicle) | upsdqhyljs(odfrohqhdv) = qegbjkhuab nktghqxlve (qpjrhgdsxv, 11.95) View more | ||||||
Phase 3 | 759 | dfuwttoymy(loiyccykiq) = fbrcbkmsgq zjqztjdywx (grdiyragni ) View more | Negative | 05 Mar 2018 | |||
Placebo | dfuwttoymy(loiyccykiq) = bsswjgzluf zjqztjdywx (grdiyragni ) View more | ||||||
Phase 3 | 744 | orleuwistq(sceaepqiba) = ucuovaaxxl ykbmtxluve (dvlcsbppjb ) View more | Negative | 05 Mar 2018 | |||
Placebo | orleuwistq(sceaepqiba) = lvqwfomfir ykbmtxluve (dvlcsbppjb ) View more | ||||||
Phase 2 | 108 | ucrgpjdncn(fdzpeoowrr) = vfwuyilfsk odjopezmjf (jmzvktovzn ) View more | Positive | 01 Jan 2017 | |||
Placebo | ucrgpjdncn(fdzpeoowrr) = eonmkozelj odjopezmjf (jmzvktovzn ) View more |