After launching in January, Japanese drug developer Renalys Pharma has now closed a JPY 6 billion ($38.4 million) series A to start a registrational study of its IgA nephropathy candidate, which it in-licensed earlier this year from Travere Therapeutics.
Renalys has rights to sparsentan in Japan, where it is initially undergoing clinical development, as well as in South Korea, Taiwan, Brunei, Cambodia, Indonesia, Laos, Malaysia, Myanmar, the Philippines, Singapore, Thailand, and Vietnam, while Travere maintains rights outside of the specified Asia countries.
The dual endothelin angiotensin receptor antagonist boasts accelerated approval in the US and conditional approval in the EU for IgA nephropathy under the name Filspari. Travere filed for a full approval with the FDA in March.
Renalys’ Phase III study of sparsentan is scheduled to start in the second quarter of the Japanese fiscal year, which runs from July to September. Data are expected in the second half of 2025.
Catalys Pacific and SR One, which co-founded Renalys, led Wednesday’s round. Other participating investors include JPS Growth Investment, Sumitomo Mitsui Trust Bank, Japan Co-Invest IV, and NVCC NO.9 Investment.
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