Amgen touts two cancer study wins with DLL3, Lumakras amid second-quarter earnings update

03 Aug 2023
Phase 1Phase 2Clinical ResultClinical Trial FailureFinancial Statement
Two cancer drugs succeeded in mid- or late-stage clinical studies, Amgen said Thursday in its second-quarter earnings announcement. “Momentum is building in the pipeline,” Amgen CFO Peter Griffith told Endpoints News , adding the biotech plans to discuss both datasets with regulators, calling a study for the DLL3-targeting drug tarlatamab “potentially registrational.” In a Phase II small cell lung cancer study, tarlatamab showed a durable response rate that “substantially exceeds what was previously reported in the Phase I study,” the $123 billion drugmaking giant said in its midyear update. But specific data were sparse in Thursday’s release; Amgen said it will present more detailed results at an upcoming medical conference.
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