J&J reports latest data on Balversa-based ‘pretzel’ therapy for bladder cancer

06 May 2024
Drug ApprovalClinical Result
Bladder cancer patients with a common mutation saw promising early results after receiving a Johnson & Johnson targeted therapy that administers the drug sold as Balversa through a slow-releasing pretzel-shaped delivery device. The treatment, known as TAR-210, delivers the bladder cancer drug slowly over time through a silicone tube called the “pretzel.” Balversa, also known as erdafitinib, is approved as an oral therapy, and hasn’t yet been cleared by the FDA for use in the device. But researchers hope delivering the medication with the device can spare patients from some of the drug’s side effects, including anemia, diarrhea, fatigue, mouth sores and hair loss. It’s similar to another experimental J&J bladder cancer treatment, TAR-200, which uses the “pretzel” to deliver chemotherapy.
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