NEW YORK, Nov. 1, 2022 /PRNewswire/ -- The phosphodiesterase (PDE) inhibitors market size is expected to grow by USD 2.86 billion from 2021 to 2026. In addition, the growth momentum of the market will accelerate at a CAGR of 5.81% during the forecast period. The market has been segmented by application (oral, topical, and other ROA) and geography (North America, Europe, Asia, and Rest of World (ROW)). Find a comprehensive report summary that describes the market size and forecast along with the research methodology.
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Technavio has announced its latest market research report titled Global Phosphodiesterase (PDE) Inhibitors Market 2022-2026 North America will lead the thermostatic radiator valve market during the forecast period. The region will account for 40% of the market's growth. The increased consumption of alcohol, tobacco, and adoption of urban lifestyle are the major factors that are contributing to the increased patient pool with lifestyle-related diseases, and thus driving the PDE inhibitorsPDE inhibitors market growth in the region during the forecast period. Get lifetime access to our Technavio Insights! Subscribe to our
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By application, the oral segment will be the largest contributor to market growth during the forecast period. The oral segment is dominated by PDE inhibitorsPDE inhibitors formulated in tablet dosage forms. Tablets are the most commonly used solid dosage forms, owing to their advantages and increasing popularity. The rising prevalence of various chronic diseases will ensure the continuous adoption of oral PDEPDE inhibitorsPDE inhibitors for their treatment, which would drive segment growth in the coming years. Learn about the contribution of each segment summarized in concise infographics and thorough descriptions.
to gain access to detailed information about each segment
One of the key factors driving the global phosphodiesterase inhibitors industry growth is the growing adoption of poor lifestyle habits, leading to chronic diseases. As per the CDC, excessive alcohol consumption accounts for approximately 88,000 deaths every year in the US. Working adults aged between 20 and 64 years account for 1 in 10 deaths due to excessive alcohol intake. CDC also estimates that nearly 2,000 people smoke their first cigarette before the age of 18 years. Of these, more than 300 people become daily cigarette smokers. Cigarette smoking is responsible for more than 480,000 deaths every year, including 41,000 deaths due to second-hand smoke. Other factors such as rapid urbanization and modernization have further led to the adoption of poor lifestyle habits, which will further increase the risk, thereby, driving the market growth. The application of novel technologies for PDE inhibitorsPDE inhibitors development is one of the key phosphodiesterase inhibitors market trends that is expected to impact the industry positively in the forecast period. PDE5 enzymes have an amino acid sequence and molecular structure similar to PDE6 and PDE11 and, hence, first-generation PDE5 inhibitors, such as sildenafil and vardenafil, are also competitive inhibitors of PDE6 and PDE11. The application of novel technologies for the development of PDE5 inhibitors is required to decrease their cross-reactivity with PDE6 and PDE11 enzymes. A similarity-based virtual screening technique, such as ZINC database, is used for this. In addition, PDE5 inhibitors, such as tadalafil, are known to block the potassium (K)-dependent HERG1 channel, the cardiac toxicity of the drug was tested through this database. The results thus obtained are of immense importance for researchers to design and develop novel, selective, and safe PDE5 inhibitors, which will further support the market growth. Identify key trends, drivers, and challenges in the market, which will help vendors improve their strategies to stay ahead of their competitors.
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Hedgehog Pathway Inhibitors Market by Indication and Geography – Forecast and Analysis 2022-2026: The hedgehog pathway inhibitors market share is expected to increase by USD 385.52 million from 2021 to 2026. Exhibit 01: Executive Summary – Chart on Market Overview
Exhibit 02: Executive Summary – Data Table on Market Overview
Exhibit 03: Executive Summary – Chart on Global Market Characteristics
Exhibit 04: Executive Summary – Chart on Market by Geography
Exhibit 05: Executive Summary – Chart on Market Segmentation by Application
Exhibit 06: Executive Summary – Chart on Incremental Growth
Exhibit 07: Executive Summary – Data Table on Incremental Growth
Exhibit 08: Executive Summary – Chart on Vendor Market Positioning
Exhibit 09: Parent market
Exhibit 10: Market Characteristics
Exhibit 11: Offerings of vendors included in the market definition
3.2 Market segment analysis
Exhibit 12: Market segments
3.4 Market outlook: Forecast for 2021-2026
Exhibit 13: Chart on Global - Market size and forecast 2021-2026 ($ million)
Exhibit 14: Data Table on Global - Market size and forecast 2021-2026 ($ million) Exhibit 15: Chart on Global Market: Year-over-year growth 2021-2026 (%)
Exhibit 16: Data Table on Global Market: Year-over-year growth 2021-2026 (%)
Exhibit 17: Five forces analysis - Comparison between 2021 and 2026
4.2 Bargaining power of buyers
Exhibit 18: Chart on Bargaining power of buyers – Impact of key factors 2021 and 2026
4.3 Bargaining power of suppliers
Exhibit 19: Bargaining power of suppliers – Impact of key factors in 2021 and 2026
4.4 Threat of new entrants
Exhibit 20: Threat of new entrants – Impact of key factors in 2021 and 2026
4.5 Threat of substitutes
Exhibit 21: Threat of substitutes – Impact of key factors in 2021 and 2026
Exhibit 22: Threat of rivalry – Impact of key factors in 2021 and 2026
Exhibit 23: Chart on Market condition - Five forces 2021 and 2026
5 Market Segmentation by Application
Exhibit 24: Chart on Application - Market share 2021-2026 (%) Exhibit 25: Data Table on Application - Market share 2021-2026 (%)
5.2 Comparison by Application
Exhibit 26: Chart on Comparison by Application
Exhibit 27: Data Table on Comparison by Application
5.3 Oral - Market size and forecast 2021-2026
Exhibit 28: Chart on Oral - Market size and forecast 2021-2026 ($ million)
Exhibit 29: Data Table on Oral - Market size and forecast 2021-2026 ($ million)
Exhibit 30: Chart on Oral - Year-over-year growth 2021-2026 (%)
Exhibit 31: Data Table on Oral - Year-over-year growth 2021-2026 (%)
5.4 Topical - Market size and forecast 2021-2026
Exhibit 32: Chart on Topical - Market size and forecast 2021-2026 ($ million) Exhibit 33: Data Table on Topical - Market size and forecast 2021-2026 ($ million)
Exhibit 34: Chart on Topical - Year-over-year growth 2021-2026 (%)
Exhibit 35: Data Table on Topical - Year-over-year growth 2021-2026 (%)
5.5 Other ROA - Market size and forecast 2021-2026
Exhibit 36: Chart on Other ROA - Market size and forecast 2021-2026 ($ million)
Exhibit 37: Data Table on Other ROA - Market size and forecast 2021-2026 ($ million)
Exhibit 38: Chart on Other ROA - Year-over-year growth 2021-2026 (%)
Exhibit 39: Data Table on Other ROA - Year-over-year growth 2021-2026 (%)
5.6 Market opportunity by Application
Exhibit 40: Market opportunity by Application ($ million)
6.1 Customer landscape overview
Exhibit 41: Analysis of price sensitivity, lifecycle, customer purchase basket, adoption rates, and purchase criteria
7.1 Geographic segmentation
Exhibit 42: Chart on Market share by geography 2021-2026 (%)
Exhibit 43: Data Table on Market share by geography 2021-2026 (%)
7.2 Geographic comparison
Exhibit 44: Chart on Geographic comparison
Exhibit 45: Data Table on Geographic comparison
7.3 North America - Market size and forecast 2021-2026
Exhibit 46: Chart on North America - Market size and forecast 2021-2026 ($ million)
Exhibit 47: Data Table on North America - Market size and forecast 2021-2026 ($ million)
Exhibit 48: Chart on North America - Year-over-year growth 2021-2026 (%)
Exhibit 49: Data Table on North America - Year-over-year growth 2021-2026 (%)
7.4 Europe - Market size and forecast 2021-2026
Exhibit 50: Chart on Europe - Market size and forecast 2021-2026 ($ million)
Exhibit 51: Data Table on Europe - Market size and forecast 2021-2026 ($ million)
Exhibit 52: Chart on Europe - Year-over-year growth 2021-2026 (%)
Exhibit 53: Data Table on Europe - Year-over-year growth 2021-2026 (%)
7.5 Asia - Market size and forecast 2021-2026
Exhibit 54: Chart on Asia - Market size and forecast 2021-2026 ($ million)
Exhibit 55: Data Table on Asia - Market size and forecast 2021-2026 ($ million)
Exhibit 56: Chart on Asia - Year-over-year growth 2021-2026 (%)
Exhibit 57: Data Table on Asia - Year-over-year growth 2021-2026 (%)
7.6 Rest of World (ROW) - Market size and forecast 2021-2026
Exhibit 58: Chart on Rest of World (ROW) - Market size and forecast 2021-2026 ($ million)
Exhibit 59: Data Table on Rest of World (ROW) - Market size and forecast 2021-2026 ($ million)
Exhibit 60: Chart on Rest of World (ROW) - Year-over-year growth 2021-2026 (%)
Exhibit 61: Data Table on Rest of World (ROW) - Year-over-year growth 2021-2026 (%)
7.7 US - Market size and forecast 2021-2026
Exhibit 62: Chart on US - Market size and forecast 2021-2026 ($ million)
Exhibit 63: Data Table on US - Market size and forecast 2021-2026 ($ million)
Exhibit 64: Chart on US - Year-over-year growth 2021-2026 (%)
Exhibit 65: Data Table on US - Year-over-year growth 2021-2026 (%)
7.8 Germany - Market size and forecast 2021-2026
Exhibit 66: Chart on Germany - Market size and forecast 2021-2026 ($ million)
Exhibit 67: Data Table on Germany - Market size and forecast 2021-2026 ($ million)
Exhibit 68: Chart on Germany - Year-over-year growth 2021-2026 (%)
Exhibit 69: Data Table on Germany - Year-over-year growth 2021-2026 (%)
7.9 UK - Market size and forecast 2021-2026
Exhibit 70: Chart on UK - Market size and forecast 2021-2026 ($ million)
Exhibit 71: Data Table on UK - Market size and forecast 2021-2026 ($ million)
Exhibit 72: Chart on UK - Year-over-year growth 2021-2026 (%)
Exhibit 73: Data Table on UK - Year-over-year growth 2021-2026 (%)
7.10 China - Market size and forecast 2021-2026
Exhibit 74: Chart on China - Market size and forecast 2021-2026 ($ million)
Exhibit 75: Data Table on China - Market size and forecast 2021-2026 ($ million)
Exhibit 76: Chart on China - Year-over-year growth 2021-2026 (%)
Exhibit 77: Data Table on China - Year-over-year growth 2021-2026 (%)
7.11 Canada - Market size and forecast 2021-2026
Exhibit 78: Chart on Canada - Market size and forecast 2021-2026 ($ million)
Exhibit 79: Data Table on Canada - Market size and forecast 2021-2026 ($ million)
Exhibit 80: Chart on Canada - Year-over-year growth 2021-2026 (%)
Exhibit 81: Data Table on Canada - Year-over-year growth 2021-2026 (%)
7.12 Market opportunity by geography
Exhibit 82: Market opportunity by geography ($ million)
8 Drivers, Challenges, and Trends
8.3 Impact of drivers and challenges
Exhibit 83: Impact of drivers and challenges in 2021 and 2026
Exhibit 84: Overview on Criticality of inputs and Factors of differentiation
Exhibit 85: Overview on factors of disruption
Exhibit 86: Impact of key risks on business
Exhibit 87: Vendors covered
10.2 Market positioning of vendors
Exhibit 88: Matrix on vendor position and classification
Exhibit 90: Bayer AG - Business segments 10.4 Cristalia laboratory
Exhibit 94: Cristalia laboratory - Product / Service
Exhibit 95: Cristalia laboratory - Key offerings
Exhibit 104: Eli Lilly and Co. - Product / Service Exhibit 105: Eli Lilly and Co. - Key offerings 11.2 Inclusions and exclusions checklist
Exhibit 126: Inclusions checklist
Exhibit 127: Exclusions checklist
11.3 Currency conversion rates for US$
Exhibit 128: Currency conversion rates for US$
11.4 Research methodology
Exhibit 129: Research methodology
Exhibit 130: Validation techniques employed for market sizing
Exhibit 131: Information sources
11.5 List of abbreviations
Exhibit 132: List of abbreviations
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