Delving into the Latest Updates on University of Kufa with Synapse

Overview

Thalassemias are a heterogeneous grouping of genetic disorders that result in dysfunctional Hb, reduced RBC life span leading to chronic anemia . Thalassemia is endemic in the Middle East. Iron chelation therapy (ICT) is one of treatment used however ICT is associated with patients adherence problem thus impacting its effectiveness .

Start Date28 Mar 2023

Sponsor / Collaborator

University of Kufa

NCT05540431 / Not yet recruitingPhase 2/3IIT

Evaluation of Protective Effect of Activated Charcoal and Probiotic Against Progression of Chronic Kidney Disease

Investigate the nephroprotective effect of Activated Charcoal and Probiotic in limiting the progression of renal impairment in patients with chronic kidney disease and improving of renal function test and phosphate level.
Condition or disease:
chronic kidney disease

Start Date25 Sep 2022

Sponsor / Collaborator

University of Kufa

NCT05100407 / CompletedNot ApplicableIIT

Evaluation of the Prevalence and Antibiotic Susceptibility Pattern of Multidrug Resistance Bacteria and Its Association With Patients' Predictive Factors

To determine the prevalence of multidrug resistance bacteria in patient with different infections
To evaluate patients' predictive risk factors of antimicrobial resistance
To assess the association between patients' factors and prevalence of MDR bacteria

Start Date01 Mar 2022

Sponsor / Collaborator

University of Kufa

100 Clinical Results associated with University of Kufa

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0 Patents (Medical) associated with University of Kufa

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4,139

Literatures (Medical) associated with University of Kufa

01 Feb 2025·Journal of Molecular Structure

Structural and functional characterization of gamma-irradiation-enhanced nanocomposites for colorectal cancer therapy

Author: Saad, Hazwani Mat ; Alhasan, Ammar ; Almayahi, Basim A. ; Sani, Siti F. Abdul ; Sim, Kae Shin ; Tajuddin, Hairul A.

The purpose of this research was to develop and evaluate a nanocomposite material for the treatment of colorectal cancer.The nanocomposite consisted of manganese-doped silver nanoparticles coated with silica (Si-Ag: Mn₃O₄).The nanocomposite was synthesized by co-precipitating silver and manganese oxide, followed by a silica coating using the Stober method.Extensive characterization was conducted to assess the morphol., optical, and stability properties.The key findings of this study are the Si-Ag: Mn₃O₄ nanocomposite exhibited unexpected and potent cytotoxicity against colorectal cancer cells, exceeding the effects of the pos. control, cisplatin.The silica coating increased the Ag: Mn ratio, further enhancing the efficacy of the nanocomposite in cancer treatment; the nanocomposite maintained cellular mobility without agglomeration or sedimentation, indicating its potential for targeted tumor destruction; and gamma irradiation of the nanocomposite further increased its cytotoxic effects on colorectal cancer cells.In conclusion, the unique combination of silver, manganese oxide, and silica in this nanocomposite framework shows great promise for advanced applications in selective cancer therapy.The nanocomposite demonstrated significant cytotoxicity against HT-29 colorectal cancer cells, particularly at a gamma dose of 5.256 kGy.The results of this study open new perspectives in biol. research, cancer treatment, and nanomedicine.

31 Dec 2024·Arab Journal of Basic and Applied Sciences

Impact of prenatal tramadol exposure on cerebral and cerebellar development and amyloid precursor protein expression in newborn mice

Author: Mubarak, Haider J. ; Philip, Anil K. ; Farhan, Thair M. ; Hadi, Najah R. ; Abid, Hussein A. ; Jamil, Dina, A. ; Mohammad, Bassim I. ; Al-Aubaidy, Hayder A. ; Kammona, Huda R.

01 Dec 2024·Current Problems in Cardiology

Effectiveness of emotional-focused coping on heart-focused anxiety in patients prior to cardiac catheterization

Review

Author: Al-Hadrawi, Hayder H ; Gatie, Baneen Kamil ; AL-Hadrawi, Hayder H.

100 Deals associated with University of Kufa

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100 Translational Medicine associated with University of Kufa

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