[Translation] Phase I clinical study of single and multiple doses of recombinant human keratinocyte growth factor-2 eye drops (rhKGF-2) in healthy Chinese adult subjects
主要目的:评价在中国健康受试者中单次、多次眼部给予rhKGF-2滴眼液后的局部(眼部)和全身的安全性和耐受性。次要目的:?评价在中国健康受试者中单次、多次眼部给予rhKGF-2滴眼液后的药代动力学(Pharmacokinetics, PK)特征。
[Translation] Primary objective: To evaluate the local (ocular) and systemic safety and tolerability of rhKGF-2 eye drops after single and multiple ocular administration in healthy Chinese subjects. Secondary objective: To evaluate the pharmacokinetic (PK) characteristics of rhKGF-2 eye drops after single and multiple ocular administration in healthy Chinese subjects.