Delving into the Latest Updates on Livzon Syntpharm Co. Ltd. Zhuhai Ftz with Synapse

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Infectious Diseases

Small molecule drug

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Disease Domain	Count

Infectious Diseases	1

Top 5 Drug Type	Count

Small molecule drug	1

Top 5 Target	Count

β-lactamase(Beta Lactamase)	1

Objective: To establish a capillary gas chromatog. method for the determination of residual solvent of cyclohexylamine in cefoxitin sodium bulk drug.Methods: The determination was performed on a DB-624 capillary column with temperature program.The injection port and detector temperature were 180°C and 250°C, resp.The carrier gas was nitrogen.Results: The linear range for cyclohexylamine was 0.4-20 μg/mL (r = 0.9995).The average recoveries were 96.7% (RSD = 1.8%).The limit of detection and limit of quantitation were 0.13 μg/mL and 0.27 μg/mL, resp.Conclusion: The method is simple and has a good accuracy.It can be used for determination of residual solvent of cyclohexylamine in cefoxitin sodium bulk drug.

Jinri Yaoxue

Determination of residual formic acid in ceftazidime pentahydrate bulk drug by gas chromatography

Author: Zhong, Baoxin ; Xiang, Yidong ; Song, Shiqiu

OBJECTIVE To establish a pre-column derivation capillary gas chromatog. method for the determination of solvent of formic acid in ceftazidime pentahydrate bulk drug.METHODS The determination was performed on a DB-WAX capillary column.The injection port and detector temperature were 200°C and 250°C, resp.The flow rate was 0.6 mL/L when the column temperature was 40°C.The carrier gas was nitrogen.RESULTS The liner range for formic acid was 0.0339-0.1017 mg/mL (r= 0.9997).The average recoveries were 98.8% (RSD = 0.9%).The limit of detection and limit of quantification were 4.7μg/mL and 15.7μg/mL, resp.CONCLUSION The method is easy to operate and has a good accuracy.It can be used for determination of residual solvent of formic acid in ceftazidime pentahydrate bulk drug.

Zhongguo Yiyao Gongye Zazhi

Identification of β-lactam antibiotics by near infrared reflectance spectrometry

Author: Yang, Chun ; Wang, Julai ; Lu, Ying ; Liu, Yuankun

Near IR reflectance spectrometry was used to identify β-lactam antibiotics and their intermediates.The results indicated that β-lactam antibiotics could be identified in glass vials without sample pretreatment.

100 Deals associated with Livzon Syntpharm Co. Ltd. Zhuhai Ftz

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100 Translational Medicine associated with Livzon Syntpharm Co. Ltd. Zhuhai Ftz

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Pipeline

Pipeline Snapshot as of 07 Nov 2024

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

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