Biolexis Therapeutics is a biotech company founded by two veterans of both small molecule drug development and life science startups. Cancer biologist Dr. David Bearss is an expert in small-molecule drug development and the use of genetic model systems in drug discovery while Dr. Hariprasad Vankayalapati, a medicinal chemist, brings extensive knowledge and experience in identifying and developing lead candidates for drug discovery. Biolexis Therapeutics is a privately held clinical-stage biopharmaceutical company dedicated to developing small molecules targeting cancers, immune-mediated, neurodegenerative, auto-immune, metabolic, and inflammatory diseases.

Disease Domain	Count

Hemic and Lymphatic Diseases	3
Neoplasms	3
Endocrinology and Metabolic Disease	1
Nervous System Diseases	1
Immune System Diseases	1

Top 5 Drug Type	Count

Small molecule drug	4
Unknown	1

Top 5 Target	Count

PIM1(Proto-oncogene serine/threonine-protein kinase Pim-1)	1
EIF2AK4(eukaryotic translation initiation factor 2 alpha kinase 4)	1
HDAC6(Histone deacetylase 6)	1
CDK9(Cyclin-dependent kinase 9)	1

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Pipeline

Pipeline Snapshot as of 01 Jul 2024

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

Discovery

Preclinical

Current Projects

Drug(Targets)	Indications	Global Highest Phase

HCI-1046 ( EIF2AK4 )	Acute Myeloid Leukemia More	Preclinical
STLS-001	Hemorrhoids More	Preclinical
BLX-0676 ( PIM1 )	Multiple Myeloma More	Preclinical
BLX-3030 ( CDK9 )	Leukemia More	Preclinical
BLX-0200 ( HDAC6 )	Amyotrophic Lateral Sclerosis 11 More	Discovery

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