Nanjing Edgar Biopharmaceutical Technology Co., Ltd.

Main study objectives: To investigate the pharmacokinetic characteristics of a single oral administration of 30 mL of acetylcysteine oral solution (test preparation, specification: 200 mL: 4 g) provided by Nanjing Aidejia Biopharmaceutical Technology Co., Ltd. and a single oral administration of 3 bags of acetylcysteine granules (reference preparation, trade name: Fulushi®; specification: 0.2 g (in terms of acetylcysteine)) certified by Hainan Zanbang Pharmaceutical Co., Ltd. in healthy subjects under fasting and postprandial conditions, to evaluate the bioequivalence and safety between the two preparations, and to provide a basis for the registration application of the test preparation. Secondary study objectives: To observe the safety of a single oral administration of the test preparation acetylcysteine oral solution (specification: 200 mL: 4 g) and the reference preparation acetylcysteine granules (trade name: Fulushi®, specification: 0.2 g) in healthy subjects under fasting and postprandial conditions.

The main purpose of the study was to examine the single oral administration of Procaterol Hydrochloride Granules (Test Preparation T, Pharmacokinetic characteristics of Procaterol Hydrochloride Dry Syrup [Reference Preparation R, Trade Name: Meptin®, Specification: 0.005% (g/g)] licensed by Otsuka Manufacturing Co., Ltd. , evaluate the bioequivalence of the two preparations, and provide a basis for the registration application of the test preparation. Secondary research purpose Observe healthy subjects taking a single oral dose of 50 μg of the test preparation Procaterol Hydrochloride Granules (specification: 25 μg) and 50 μg of the reference preparation Procaterol Hydrochloride Dry Syrup under fasting and postprandial conditions [(trade name: Meptin®, Specification: 0.005% (g/g)] safety.