Fu Jen Catholic University

Dr. Wang appointed by the OBI Pharma Board of Directors as Chief Executive Officer to lead OBI Pharma with a vision and to bring innovative cancer therapies to patients globally. She brings a wealth of global executive management, regulatory, and drug approval experience in five therapeutic areas including cancer drug development, during a ~ 30-year tenure at Bristol Myers Squibb Company. TAIPEI, Taiwan, June 02, 2023 (GLOBE NEWSWIRE) -- OBI Pharma, Inc. (TPEx: 4174) | Effective immediately, the OBI Pharma Board of Directors have appointed Heidi Wang, Ph.D. as Chief Executive Officer, a position previously held by Chairman and CEO, Yun Yen, MD. “We are excited that Dr. Wang has been appointed CEO of OBI Pharma to bring strategic vision and lead the organization with our innovative cancer therapeutics pipeline, towards successful development and potentially regulatory approvals worldwide. Dr. Wang brings a wealth of global executive management, scientific knowledge, development, and regulatory experience during her ~30 years tenure at Bristol Myers Squibb company (BMS)™. “I am excited to contribute to the future direction and success of OBI Pharma as a potential leading cancer therapeutics biopharma company. I am impressed with the dedication and accomplishments of the organization to date. Additionally, with OBI’s innovative cancer pipeline under clinical trials to address unmet medical needs, it is an exciting time to join the organization,” stated Dr. Wang. Dr. Wang will report to Yun Yen, M.D, OBI Pharma’s Chairman of the Board. Prior to joining OBI Pharma, she was Vice President, Head of Global Regulatory Sciences Oncology. Additionally, she has held executive and senior management roles of increasing responsibilities as Interim Head of R&D and Regulatory in China, US and International Regulatory Strategy, Global Product Labeling, Medical Communications, and Research Discovery. Dr. Wang has received the following degrees: Ph.D. and M.S. degrees at the University of Notre Dame (South Bend, IN) and B.S. degree at Fu-Jen University (Taipei, Taiwan). She also received postdoctoral training in cancer biology at The Cold Spring Harbor Laboratory (Cold Spring Harbor, NY). She has won numerous awards and authored numerous scientific publications during her career. About OBI Pharma OBI Pharma, Inc., is a Taiwanese biopharmaceutical company that was established in 2002. Its mission is to develop and license novel therapeutic agents for important unmet medical needs against promising cancer targets such as the Globo series of glycosphingolipids (including Globo H and SSEA-4), AKR1C3, Trop-2, and others. The company’s novel first-in-class immuno-oncology portfolio targeting Globo H includes: two Globo H active immunotherapy vaccines, Adagloxad Simolenin (formerly OBI-822) and OBI 833; the Globo H antibody-drug conjugate (ADC) OBI-999, and the Globo H CAR T-cell therapeutic OBI-R007. OBI’s pipeline also includes the first-in-class AKR1C3-targeted small-molecule prodrug OBI-3424, which selectively releases a potent DNA-alkylating antitumor agent in the presence of the aldo-keto reductase 1C3 (AKR1C3) enzyme, and the novel next generation Trop-2 ADC, R992, which is designed to target 1st generation Trop-2-ADC resistant cancers. Additional information can be found at Forward-Looking Statements Statements included in this press release that are not a description of historical facts are forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Such forward-looking statements include, but are not limited to, statements about future clinical trials, results and the timing of such trials and results. Such risk factors are identified and discussed from time to time in OBI Pharma’s reports and presentations, including OBI Pharma’s filings with the Taiwan Securities and Futures Bureau. COMPANY CONTACT: Kevin Poulos OBI Pharma USA, Inc. 1.619.537.7698 Ext. 102 kpoulos@obipharmausa.com

The COVID-19 pandemic has dramatically transformed the way healthcare is delivered, and its impact on hospital design will be felt for many years to come. Here we round up 10 hospitals - some already built, some under construction - with advanced technologies and forward-thinking designs that will enable them to meet the healthcare challenges of the future. 10. New Odense University Hospital, Odense Denmark's hospitals are currently undergoing a programme of modernisation, which will see them become more specialised and have an increased focus on outpatient services. Another important part of this is making them more sustainable, by increasing digitalisation and deploying energy efficient medical equipment and lighting systems. The New Odense University Hospital is currently under construction, but once it opens in 2022 it will be a flagship for the country, with an efficient water management system and natural air ventilation. A large solar panel on the roof is already supplying one third of the energy needed to build the hospital, and it is estimated it will provide one fifth of the power for operations once the building is finished. 9. Neuro Spinal Hospital and Radiosurgery Centre, Dubai This new hospital in the Dubai Science Park has state-of-the-art technology for spinal, neurosurgical, neurological, orthopaedic, radiosurgery and cancer treatments. Its 114 patient beds include smart patient rooms, and this is also the first hospital in the UAE to deploy surgical robots and the CyberKnife System - a non-invasive alternative to surgery for inoperable or surgically complex tumours. 8. University of Virginia University Hospital, Charlottesville Since opening in 2020 this hospital has won several awards for its design and facilities. Its architecture places the emphasis on nature, and what sets it apart is its unique shape, which enables patient rooms to have views of the hospital's planted roofs, as well as scenic views across the nearby valley. Staff break rooms have similar views with the aim of promoting wellbeing among the workforce. Among its other accolades is featuring on Newsweek's Best Maternity Hospitals 2021 list. 7. Carlisle Healthcare Hub, Carlisle Construction recently began on the Carlisle Healthcare Hub, which has the goal of becoming the most sustainable healthcare centre in the UK once it's open. It is being designed to be carbon neutral and meet the BREEAM Outstanding criteria, a sustainability benchmark for buildings. All of the facilities' energy will be from renewable sources thanks to roof top solar panels and battery storage, plus there will be a heat recovery ventilation system in place of a traditional, energy-intensive heating system. 6. Bayalpata Hospital, Nepal This hospital located in a remote part of Nepal where access to healthcare is extremely limited (it's a 10 hour drive away from the nearest airport) has been constructed using rammed earth, in other words natural raw materials including earth, chalk and gravel. This technique was chosen to ensure the hospital is sustainable and costs of building were kept low. The natural materials have been used throughout the facility, giving it a non-clinical appearance, and care has been taken to ensure there's plenty of natural light. 5. Midland Metropolitan University Hospital, Birmingham This new hospital has been labelled a "digital super hospital", and once open in 2022 it is expected to be one of the most digitally advanced in the UK. As well as utilising MRI and ultrasound machines by Siemens Healthineers, the building will deploy Schneider Electric’s EcoStruxure™ solutions for its power and control systems. This uses IoT technology to reduce energy consumption, connecting medical devices and providing advanced analytics. The hospital is also being designed to ensure it is dementia-friendly. 4. Fu Jen Catholic University Hospital, New Taipei City Architects Miniwiz and Fu Jen Catholic University Hospital have designed a modular ward that hospitals can deploy for COVID-19 cases. The ward uses recycled aluminium panels that can quickly be assembled within the hospital or to create a mobile ward in a nearby area. The panels have an anti-bacterial coating, and include an ultraviolet self-cleaning system that destroys bacteria and viruses. Once interlocked, they create a negative-pressure environment which enables ventilation. The materials are lightweight, enabling transportation over long distances. 3. Ankara City Hospital, Ankara Ankara City Hospital is one of the largest in the world, with around 4,000 beds and 130 operating rooms. A smart building management platform enables the control of the hospital's internal systems, which includes almost 800,000 data points for the building's infrastructure to run without problems. Automation technology from Siemens Healthineers is deployed in the hospital's labs, so that 140,000 tests can be carried out per day. 2. Sidre Medicine and Research Center, Doha This Qatari hospital is paperless and practically wireless, with its all-digital facilities deploying robotics, computer-aided surgery and digital imaging technology. Clinicians use mobile devices which enable them to monitor patients wherever they are, as well as scan bar codes on medication and photograph patient injuries. All this information is stored in a secure cloud server. As well as the focus on advanced technologies, attention has been paid to the natural environment, with the design maximising natural light, along with an indoor healing garden and water features. 1. Chase Farm Hospital, London London's Chase Farm Hospital is one of the most digitally advanced hospitals in the world. In 2019 it achieved HIMSS Level 6, a rating that assesses the electronic medical record (EMR) systems in hospitals on a scale of 0 to 7. The EMR here captures test results, prescriptions and vital signs, and self-check in kiosks enable patients to check themselves in at reception. Mobile devices are in use by staff throughout the hospital to quickly capture and access information, and a mobile handset nurse call system lets patients call a nurse without disturbing other patients.