Nuevocor Pte Ltd.

SINGAPORE and PHILADELPHIA, April 9, 2024 /PRNewswire/ -- Nuevocor, a pre-clinical stage biotechnology company dedicated to developing novel medicines to treat cardiomyopathies with aberrant mechanobiology, today announces the appointment of Dr. John Lee, MD, PhD, as its Chief Medical Officer. Dr. Lee is a life science executive with experience spanning from early drug discovery to late-stage clinical development. Dr. John Lee is a board-certified cardiologist who brings over 15 years of clinical development and regulatory expertise to Nuevocor. Dr. Lee was most recently the Chief Medical Officer of PhaseBio Pharmaceuticals, a publicly listed biotech, where he led Phase I-III development of its clinical programs. Prior to PhaseBio, Dr. Lee was the Vice President, Global Head, Cardiovascular Center of Excellence at Quintiles, where he was responsible for developing and implementing the cardiovascular therapeutic area business growth strategy and also represented their cardiovascular therapeutic expertise across the broader enterprise and in the global marketplace. Dr. Lee also served as Executive Director, Discovery Medicine at Bristol-Myers Squibb ("BMS"), where he was responsible for leading the team that provided medical, clinical, scientific, regulatory and R&D advisory expertise in cardiovascular drug development across BMS. Having held key leadership roles in both biotech and pharmaceutical sectors, Dr. Lee is poised to spearhead Nuevocor's clinical development strategy and advance its innovative therapies for LMNA DCM through rigorous clinical development oversight and execution. "Dr. Lee's appointment marks a significant milestone for Nuevocor," said Dr. Yann Chong Tan, PhD, CEO and Co-Founder of Nuevocor. "His extensive experience and proven track record in clinical development make him the ideal candidate to lead our clinical development team. His leadership will be instrumental in furthering our commitment to advancing science and translating it into therapies that will make a real difference in patients' lives." "I am honored to join Nuevocor at this pivotal moment," said Dr. John Lee. "The opportunity to lead the clinical development efforts for the LMNA DCM program is incredibly motivating. I look forward to collaborating with the talented team at Nuevocor to bring potentially life-changing therapies to patients." About Nuevocor Nuevocor is a biotechnology company that is pioneering an innovative pathway-centric approach to developing genetic medicines for heart conditions known as cardiomyopathies. By harnessing our PrOSIA™ mechanobiology platform, Nuevocor designs genetic medicines to target the biomechanical root cause of these diseases. Nuevocor's approach surpasses the limitations of traditional gene therapy, which focuses on individual gene mutations, to treat defects within shared disease pathways across multiple genetic cardiomyopathies. This enables us to extend our impact to broader patient populations. SOURCE Nuevocor

SINGAPORE, Nov. 7, 2023 /PRNewswire/ -- Nuevocor, a pre-clinical stage biotechnology company focused on developing cardiac genetic medicines through a unique platform to understand the mechanobiological causes of disease, announced today a pair of presentations at two major meetings, the European Society for Gene and Cell Therapy (ESGCT) 30th Annual Congress, and the American Heart Association (AHA) Scientific Sessions 2023. The poster presentations showcase optimization efforts for Nuevocor's first-in-class lead programme using a mechanobiology-based approach to treat LMNA-associated dilated cardiomyopathy. At the ESGCT Congress on 24 – 27 October, 2023 in Brussels, Belgium, Nuevocor co-founder and Chief Executive Officer, Dr. Yann Chong Tan, presented a poster (P613) entitled "An AAV gene therapy for LMNA dilated cardiomyopathy via disruption of the LINC complex." At the AHA Scientific Sessions meeting in Philadelphia, Pennsylvania, USA, Nuevocor Chief Medical Officer, Dr John Lee, will present a poster (Sa3004) entitled "AAV-Mediated LINC Complex Uncoupling Ameliorates Pathology in a Mouse Model of LMNA Dilated Cardiomyopathy" on Saturday, November 11, 2023 11:30 AM - 12:45 PM at Zone 3, Science and Technology Hall, Level 200 of the Pennsylvania Convention Center. For more information on the meetings, please visit the respective conference websites. About Nuevocor Nuevocor is a biotechnology company that is pioneering an innovative pathway-centric approach to developing genetic medicines for heart conditions known as cardiomyopathies. By harnessing our PrOSIA mechanobiology platform, Nuevocor designs genetic medicines to target the biomechanical root cause of these diseases. Nuevocor's approach surpasses the limitations of traditional gene therapy, which focuses on individual gene mutations, to treat defects within shared disease pathways across multiple genetic cardiomyopathies. This enables us to extend our impact to broader patient populations. SOURCE Nuevocor

SINGAPORE, Dec. 21, 2022 /PRNewswire/ -- Nuevocor, a pre-clinical stage cardiac gene therapy company, announced today that it will be presenting at the Biotech Showcase during JPM week, taking place in San Francisco, CA, USA from January 9 to 11, 2023. Nuevocor will also be giving an oral presentation on new pre-clinical data for its LMNA cardiac gene therapy programme at the Keystone Symposium on Heart Development and Disease, taking place in Santa Fe, NM, USA from February 12 to 15, 2023. Details of the presentations are as follows: Biotech Showcase Date: Tuesday, January 10, 2023 Time: 3:00PM PST Location: Hilton San Francisco Union Square, Franciscan B (Ballroom Level) Presenter: Yann Chong Tan, PhD, Founder and CEO, Nuevocor Keystone Symposia on Heart Development and Disease: From Genes to Cures Date: Tuesday, February 14, 2023 Time: 2:30PM MST Location: Eldorado Hotel, Santa Fe Session: Workshop 2 – Resolving the Genotype-Phenotype Conundrum in Congenital Heart Disease and Inherited Cardiomyopathies Title: Targeting the LINC Complex with AAV Gene Therapy Extends Lifespan and Preserves Cardiac Function in a Mouse Model of LMNA Dilated Cardiomyopathy Presenter: Yin Loon Lee, PhD, Founder and Senior Director, Biology, Nuevocor For more information on the meetings, please visit the respective conference websites. About Nuevocor Nuevocor is a biotechnology company developing targeted gene therapies to restore heart function through a deep understanding of fundamental mechanisms underlying genetic cardiac diseases. Nuevocor is founded and advised by leaders in mechanobiology, cardiac disease and gene therapy. Their lead candidate treats the underlying biomechanical cause of LMNA dilated cardiomyopathy, while their PrOSIA mechanobiology platform enables target discovery and validation for additional genetic cardiomyopathies. SOURCE Nuevocor