Guangdong Zhongrun Drug Research and Development Co., Ltd.

Primary objective: To evaluate the effectiveness of dexketoprofen tromethamine injection in the treatment of postoperative pain after abdominal and orthopedic surgery. Secondary objective: To evaluate the safety of dexketoprofen tromethamine injection in the treatment of postoperative pain after abdominal and orthopedic surgery.

Primary objective: To evaluate the pharmacokinetic characteristics of dexketoprofen tromethamine injection after single and multiple administrations in healthy Chinese subjects. Secondary objective: To evaluate the safety of dexketoprofen tromethamine injection after single and multiple administrations in healthy Chinese subjects.

Primary objective: To study the pharmacokinetics of the test preparation trazodone hydrochloride tablets and the reference preparation trazodone hydrochloride tablets (specification: 100 mg) in healthy adult subjects after a single oral administration in fasting and postprandial states, and to evaluate the bioequivalence of the two preparations. Secondary objective: To evaluate the safety of the test preparation (T) trazodone hydrochloride tablets and the reference preparation (R) trazodone hydrochloride tablets after a single oral administration in healthy subjects after fasting and postprandial states.