[Translation] A randomized, double-blind, placebo-controlled, multicenter clinical trial to evaluate the efficacy and safety of the study drug in the treatment of acute closed soft tissue injuries

(1）评价紫金透骨喷雾剂治疗急性闭合性软组织损伤(关节扭伤)(气滞血瘀证)的有效性 (2) 探索紫金透骨喷雾剂治疗急性闭合性软组织损伤(关节扭伤)(气滞血瘀证)的最佳给药浓度 (3) 评价紫金透骨喷雾剂治疗急性闭合性软组织损伤(关节扭伤)(气滞血瘀证)的安全性

[Translation]

(1) Evaluate the effectiveness of Zijin Penetrating Bone Spray in the treatment of acute closed soft tissue injury (joint sprain) (Qi stagnation and blood stasis syndrome) (2) Explore the optimal dosing concentration of Zijin Penetrating Bone Spray in the treatment of acute closed soft tissue injury (joint sprain) (Qi stagnation and blood stasis syndrome) (3) Evaluate the safety of Zijin Penetrating Bone Spray in the treatment of acute closed soft tissue injury (joint sprain) (Qi stagnation and blood stasis syndrome)

Start Date-

Sponsor / Collaborator

Guiyang Medical College

CTR20190447

/ CompletedPhase 3

珍珠滴丸治疗复发性口腔溃疡心脾积热证的有效性和安全性的随机、双盲、安慰剂平行对照、多中心III期临床试验

[Translation] A randomized, double-blind, placebo-controlled, multicenter phase III clinical trial on the efficacy and safety of Zhenzhu Drop Pills in the treatment of recurrent oral ulcers with heart and spleen heat accumulation syndrome

以靶溃疡愈合时间为主要疗效指标，确证珍珠滴丸治疗复发性口腔溃疡（心脾积热证）的有效性和安全性，为本品注册审查提供依据。

[Translation]

Taking target ulcer healing time as the main efficacy indicator, the effectiveness and safety of Pearl Drops in the treatment of recurrent oral ulcers (heart and spleen heat accumulation syndrome) were confirmed, providing a basis for the registration review of this product.

Start Date16 Apr 2019

Sponsor / Collaborator

Guiyang Medical College

[+1]

CTR20150107

/ CompletedPhase 2

珍珠滴丸治疗复发性口腔溃疡（心脾积热证）有效性及安全性的随机、双盲、剂量平行对照、多中心Ⅱ期临床试验

[Translation] A randomized, double-blind, dose-controlled, multicenter phase II clinical trial on the efficacy and safety of Zhenzhu Drop Pills in the treatment of recurrent oral ulcers (heart and spleen heat accumulation syndrome)

从靶溃疡愈合率、愈合时间、疼痛消失率、疼痛消失时间等方面，初步评价珍珠滴丸治疗复发性口腔溃疡（心脾积热证）的有效性及安全性，同时进行剂量探索，初步评价剂量与疗效及安全性的关系，为下一阶段临床试验设计提供依据。

[Translation]

The effectiveness and safety of Pearl Drops in the treatment of recurrent oral ulcers (heart and spleen heat accumulation syndrome) were preliminarily evaluated in terms of target ulcer healing rate, healing time, pain disappearance rate, pain disappearance time, etc. At the same time, dose exploration was carried out to preliminarily evaluate the relationship between dose and efficacy and safety, providing a basis for the design of the next stage of clinical trials.

Start Date22 Apr 2015

Sponsor / Collaborator

Guiyang Medical College

[+1]

100 Clinical Results associated with Guiyang Medical College

0 Patents (Medical) associated with Guiyang Medical College

2,600

Literatures (Medical) associated with Guiyang Medical College

01 Apr 2021·Biotechnology Letters

Correction to: Bio-electrospraying is a safe technology for delivering human adipose-derived stem cells

Author: Lin, Yunfeng ; Sun, Bo ; He, Zhixu ; Zhang, Yi ; Ye, Chuan ; Tang, Jin ; Yang, Long ; Zhao, Baoping ; Liu, Jielin ; Ma, Minxian ; Ren, Houxiang

In the published version of Fig. 2, images at 1 h 0 kV and 10 kV overlap with image 5 kV.The corrected version of Fig. 2 shows new images for 1 h-0 kV and 10 kV.The authors regret their oversight during figure assembly and would like to sincerely apologize for this error.This unintentional error has no bearing on the article′s scientific conclusion.

01 Aug 2020·European review for medical and pharmacological sciences

Psychological support and the COVID-19 - A short report.

Article

Author: L. Ye ; J. Chen ; Y. R. Cheng ; G. F. Chen ; M. W. Wang ; F. Zhang ; M. Y. Zhou ; Z. H. Feng

OBJECTIVEThe World Health Organization reported a cluster of cases of pneumonia of unknown cause detected on December 31, 2019 in China. Unfortunately, a 34-year-old Italian nurse has committed suicide after testing positive for coronavirus. It was the second case of suicide by a nurse in an Italian hospital and occurred only a few days after the first suicide. These consecutive suicides have aroused concern, and it is necessary to investigate the psychological issues of the medical staff in Italy regarding the COVID-19.

01 Jun 2020·International Journal of Systematic and Evolutionary MicrobiologyQ3 · BIOLOGY

Gordonia crocea sp. nov. and Gordonia spumicola sp. nov. isolated from sludge of a wastewater treatment plant

Q3 · BIOLOGY

Article

Author: Kang, Yingqian ; Hoshino, Yasutaka ; Yaguchi, Takashi ; Tamura, Tomohiko ; Mikami, Yuzuru ; Gonoi, Tohru ; Hamada, Moriyuki ; Saito, Satomi

Two novel actinobacteria, designated NBRC 107696T and NBRC 107697T, were isolated from sludge samples from a wastewater treatment plant and their taxonomic positions were investigated by a polyphasic approach. The cells of the strains were aerobic, rod-shaped, non-motile and non-endospore-forming. The strains contained glutamic acid, alanine and meso-diaminopimelic acid in the peptidoglycan. Galactose and arabinose were detected as cell-wall sugars. The predominant menaquinone was identified as MK-9(H2) and the major fatty acids were C16 : 0, C18 : 1ω9c and C16 : 1ω7c. The DNA G+C contents of NBRC 107696T and NBRC 107697T were 68.07 and 68.99 mol%, respectively. Phylogenetic analyses based on 16S rRNA gene sequence comparisons revealed that NBRC 107696T and NBRC 107697T were a clade with members of the genus

Gordonia

. The highest 16S rRNA gene sequence similarity values were obtained with

Gordonia araii

IFM 10211T (98.9 %) for NBRC 107697T, and

Gordonia malaquae

IMMIB WWCC-22T,

Gordonia neofelifaecis

AD-6T and

Gordonia humi

CC-12301T (98.1 %) for NBRC 107696T, respectively. The digital DNA–DNA relatedness data coupled with the combination of genotypic and phenotypic data indicated that the two strains are representatives of two novel separate species. The names proposed to accommodate these two strains are Gordonia spumicola sp. nov. and Gordonia crocea sp. nov., and the type strains are NBRC 107696T (=IFM 10067T=TBRC 11239T) and NBRC 107697T (=IFM 10881T=TBRC 11240T), respectively.

100 Deals associated with Guiyang Medical College

100 Translational Medicine associated with Guiyang Medical College

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Current Projects

Drug(Targets)	Indications	Global Highest Phase

Zijin Tougu Spray	Soft Tissue Injuries More	Phase 2
Pearl Dropping Pills	Oral Ulcer More	Pending
Danlanxian Boron Therapy Fluoride Capsule	-	Pending

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