100 Clinical Results associated with Vitrisa Therapeutics, Inc.
0 Patents (Medical) associated with Vitrisa Therapeutics, Inc.
02 Aug 2019·Science advancesQ1 · CROSS-FIELD
Covalently tethering siRNA to hydrogels for localized, controlled release and gene silencing
Q1 · CROSS-FIELD
ArticleOA
Author: Huynh, Cong Truc ; Levy, Mathew ; Wilner, Samantha E. ; Maier, Keith E. ; Gilewski, Alex ; Alsberg, Eben ; Kwon, Nicholas ; Nguyen, Minh Khanh
Covalently tethering RNA to hydrogel provides the prolonged presentation of RNA for locally sustained cellular gene silencing.
01 May 2019·Cell chemical biologyQ1 · BIOLOGY
To PEGylate or Not To PEGylate Therapeutics?
Q1 · BIOLOGY
Article
Author: Maier, Keith E ; Levy, Matthew ; Rusconi, Christopher P
PEGylation is a common modulator of pharmacokinetics for therapeutic agents in vivo. In this issue of Cell Chemical Biology, Moreno et al. (2019) show anti-PEG antibodies may directly inhibit the activity of a PEGylated aptamer, RB006, both in vitro and in vivo, and the issues surrounding anti-PEG antibodies are discussed.
01 Jun 2018·Nucleic acid therapeutics
RNA Therapeutics (Almost) Comes of Age: Targeting, Delivery and Endosomal Escape
Author: Levy, Matthew ; Dowdy, Steven F.
100 Deals associated with Vitrisa Therapeutics, Inc.
100 Translational Medicine associated with Vitrisa Therapeutics, Inc.