Fujian Gutian Pharmaceutical Co., Ltd.

The main purpose of the study is to use the adenosine cobalamin capsule (trade name: Hycobal, specification: 0.5 mg) of Eisai Co., Ltd. as the reference preparation and the adenosine cobalamin tablet (specification: 0.25 mg) provided by Fujian Gutian Pharmaceutical Co., Ltd. as the test preparation. A randomized, open, single-dose, two-period double crossover design was used to compare the pharmacokinetics of the two preparations in the fasting and postprandial states in healthy Chinese subjects and evaluate the bioequivalence. Secondary purpose of the study: To evaluate the safety of the oral test preparation adenosine cobalamin tablet (specification: 0.25 mg) and the reference preparation adenosine cobalamin capsule (trade name: Hycobal, specification: 0.5 mg) in healthy Chinese subjects.