[Translation] A Phase I clinical trial to evaluate the safety, tolerability, pharmacokinetic characteristics, immunogenicity and preliminary anti-tumor activity of NBL-028 for injection in subjects with advanced solid tumors
主要研究目的:
 ̄ 评价NBL-028在晚期实体瘤受试者中的安全性和耐受性
 ̄ 确定NBL-028的最大耐受剂量(MTD)(如有)、后续推荐剂量和给药方案 次要研究目的:
 ̄ 评价NBL-028在晚期实体瘤受试者中的药代动力学(PK)特征
 ̄ 评价NBL-028在晚期实体瘤受试者中的初步抗肿瘤活性
 ̄ 评价NBL-028在晚期实体瘤受试者中的免疫原性
[Translation] Main research purposes:
 ̄ To evaluate the safety and tolerability of NBL-028 in subjects with advanced solid tumors
 ̄ Determine the maximum tolerated dose (MTD) of NBL-028 (if any), subsequent recommended dose and dosing regimen. Secondary study objectives:
 ̄ To evaluate the pharmacokinetic (PK) characteristics of NBL-028 in subjects with advanced solid tumors
 ̄ To evaluate the preliminary anti-tumor activity of NBL-028 in subjects with advanced solid tumors
 ̄ Evaluation of the immunogenicity of NBL-028 in subjects with advanced solid tumors