The MediMabBio platform employs systems biology and advanced immunological methods to develop immuno-oncology drugs that effectively target various solid tumors. This platform utilizes rational drug design principles in the discovery of antibodies for large molecule therapeutic development.

Disease Domain	Count

Neoplasms	4
Immune System Diseases	2

Top 5 Drug Type	Count

Monoclonal antibody	2
Antibody fusion proteins	2
Antibody	1
Bispecific antibody	1

Top 5 Target	Count

GITR(Glucocorticoid-induced tumor necrosis factor receptor-related protein)	2
TIGIT(T cell immunoglobulin and ITIM domains)	1
GITR x IL-15	1
IL-15 x TIGIT	1

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Pipeline

Pipeline Snapshot as of 26 Nov 2024

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

Discovery

Preclinical

Current Projects

Drug(Targets)	Indications	Global Highest Phase

MFA-011 ( IL-15 x TIGIT )	Neoplasms More	Preclinical
MFA 031 ( GITR )	Autoimmune Diseases More	Preclinical
MMB-102 ( GITR )	Neoplasms More	Discovery
MFA-021 ( GITR x IL-15 )	Neoplasms More	Discovery
MMB-301	Autoimmune Diseases More	Discovery

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