Istanbul Medipol University

This study introduces and evaluates the unilateral convex sliding-growing rod (UCSGR) technique, a novel growth-guiding approach for early-onset scoliosis (EOS). The UCSGR aims to achieve deformity correction while preserving spinal growth and minimizing morbidity by using instrumentation solely on the convex side. A retrospective analysis was performed on EOS patients treated with UCSGR between 2018 and 2022 at a tertiary spine center. Eighteen patients were screened; 11 met inclusion criteria and completed greater than or equal to 24 months of follow-up. Clinical and radiographic outcomes—including Cobb angle, annual T1–S1 spinal growth, operative parameters, and complications—were analyzed. Curve flexibility and morphology were assessed on preoperative bending films. The cohort (mean age: 4.9 years, range: 3–7) included congenital (36.4%), spina-bifida–associated (27.3%), and juvenile idiopathic scoliosis (36.4%). Mean follow-up was 47.3 months. The average Cobb angle improved from 69.7° preoperatively to 26.4° postoperatively, yielding 63.5% correction ( P = 0.018). Annual spinal growth averaged 9.8 mm. Mean operative time was 203 min, and blood loss 225 ml. Two complications occurred—one rod fracture requiring revision and one superficial infection treated conservatively. No neurological deficits or spontaneous fusion were observed. The UCSGR technique provides substantial deformity correction with maintained spinal growth and a low complication rate. By leveraging convex-side biomechanics while preserving concave structures, it offers a promising alternative to bilateral growth-friendly constructs. Multicenter studies with longer follow-up are needed to confirm its long-term safety and efficacy.

This randomized controlled trial compared the effects of a barrier cream containing propolis, beeswax, queen bee larvae, and vegetable oil (barrier cream 1) with those of zinc oxide (barrier cream 2) and olive oil on the healing of mild diaper dermatitis (DD).

A single-blind, parallel-group, pretest-posttest, repeated-measures randomized controlled trial was conducted. The study included infants aged 1-6 months diagnosed with mild DD, who were recruited from three family health centers and a pediatric outpatient clinic in a public hospital in a district of the Mediterranean Region of Türkiye. Data were analysed using descriptive statistics, one-way analysis of variance, chi-square, Bonferroni correction, and generalized estimating equations with multiple logistic regression.

The mean DD severity score on days 1, 2, and 3 was lower in the barrier cream 1 group than in the barrier cream 2 and olive oil groups. The mean DD severity score on day 2 of the babies in the barrier cream 1 group was significantly lower than in the other groups (p = .012). Compared to olive oil, barrier cream 1 was 2.54 times (p = .004) more effective, and barrier cream 2 was 1.43 times more effective (p = .192) in improving DD.

Barrier cream 1, a formulation containing propolis, beeswax, queen bee larvae, and vegetable oil, demonstrated superior effectiveness in treating mild DD in infants compared to barrier cream 2 and olive oil.

Interventions aligned with the ABCDE model positively influenced healing outcomes and enhanced parental satisfaction.

To present the outcomes of topography-guided opposing dual-segment KeraNatural implantation in patients with keratoconus with symmetrical corneal cones.

This study evaluated 6 eyes from 5 patients who had undergone dual allogeneic intrastromal ring segment (corneal allogeneic intrastromal ring segment) opposite horizontal implantation surgery based on topographic cone location with a follow-up period ranging from 6 months to 3 years. Preoperative and postoperative measurements, including visual acuity, refractive, topographic keratometric values, and central corneal thickness, were analyzed.

Corrected distance visual acuity increased from 0.93 ± 0.58 preoperatively to 0.33 ± 0.14 postoperatively and Kmax decreased from 57.87 ± 1.87 to 55.47 ± 1.62 diopters. No significant complications were reported during the follow-up period.

This study investigates the outcomes of dual KeraNatural implantation in patients with keratoconus with symmetrical cones. The findings from this study may yield enhanced outcomes, necessitating additional exploration and possible implementation as a new standard in keratoconus surgery.